PRKD3 and MYH3

Data Source:
BioGRID (two hybrid)

		PRKD3	MYH3
Description		protein kinase D3	myosin heavy chain 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Membrane	Cytosol Muscle Myosin Complex Sarcomere Myosin Filament Extracellular Exosome
	Molecular Function	Protein Kinase C Activity Calcium-dependent Protein Kinase C Activity Protein Binding ATP Binding Kinase Activity Metal Ion Binding	Microfilament Motor Activity Calmodulin Binding ATP Binding ATPase Activity Myosin Phosphatase Activity Actin Filament Binding
	Biological Process	Protein Phosphorylation Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Sphingolipid Biosynthetic Process Protein Kinase D Signaling	Skeletal Muscle Contraction Protein Dephosphorylation Muscle Organ Development Actin Filament-based Movement Muscle Filament Sliding Embryonic Limb Morphogenesis Sarcomere Organization ATP Metabolic Process Face Morphogenesis
Pathways		Sphingolipid de novo biosynthesis	Striated Muscle Contraction
Drugs
Diseases			Distal arthrogryposis (DA)
GWAS		Body mass index ( 28892062) Chronic lymphocytic leukemia ( 28165464 24292274) Diastolic blood pressure ( 27841878) Heel bone mineral density ( 30598549) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494) Pulse pressure ( 27841878) Schizophrenia ( 23974872) Systolic blood pressure ( 28135244 27841878)	Post bronchodilator percent predicted FEV1 in smoking ( 30068317) Relative hand skill in reading disability ( 24068947)
Interacting Genes		12 interacting genes: BCL6 DLAT GSK3A IKBKG KPNA2 KPNB1 MYH3 NUDT3 POLL SKA2 TAF1 VAMP2	9 interacting genes: APPL1 CLIP4 DYSF LAMTOR5 OPTN PPP1R7 PRKD3 SNAPIN TULP3
Entrez ID		23683	4621
HPRD ID		06151	01172
Ensembl ID		ENSG00000115825	ENSG00000109063
Uniprot IDs		O94806	P11055 Q5GJ67
PDB IDs		2D9Z
Enriched GO Terms of Interacting Partners?
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