PRKD3 and SKA2

Data Source:
BioGRID (two hybrid)

		PRKD3	SKA2
Description		protein kinase D3	spindle and kinetochore associated complex subunit 2
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Membrane	Condensed Chromosome Outer Kinetochore Cytosol Spindle Microtubule
	Molecular Function	Protein Kinase C Activity Calcium-dependent Protein Kinase C Activity Protein Binding ATP Binding Kinase Activity Metal Ion Binding	Protein Binding Microtubule Binding
	Biological Process	Protein Phosphorylation Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Sphingolipid Biosynthetic Process Protein Kinase D Signaling	Mitotic Cell Cycle Chromosome Segregation Regulation Of Microtubule Polymerization Or Depolymerization Cell Division
Pathways		Sphingolipid de novo biosynthesis	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Body mass index ( 28892062) Chronic lymphocytic leukemia ( 28165464 24292274) Diastolic blood pressure ( 27841878) Heel bone mineral density ( 30598549) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494) Pulse pressure ( 27841878) Schizophrenia ( 23974872) Systolic blood pressure ( 28135244 27841878)	Cognitive function ( 25644384) Refractive error ( 32231278) Testicular germ cell tumor ( 23666239)
Interacting Genes		12 interacting genes: BCL6 DLAT GSK3A IKBKG KPNA2 KPNB1 MYH3 NUDT3 POLL SKA2 TAF1 VAMP2	6 interacting genes: HMOX2 IFT57 PRKD3 RALY SKA1 SPC24
Entrez ID		23683	348235
HPRD ID		06151	13306
Ensembl ID		ENSG00000115825	ENSG00000182628
Uniprot IDs		O94806	J3KSP0 Q8WVK7
PDB IDs		2D9Z	4AJ5
Enriched GO Terms of Interacting Partners?
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