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SLC7A11 and BAAT
Data Source:
HPRD
(in vitro)
SLC7A11
BAAT
Description
solute carrier family 7 member 11
bile acid-CoA:amino acid N-acyltransferase
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Rough Endoplasmic Reticulum
Cytoskeleton
Plasma Membrane
Cell Surface
Integral Component Of Membrane
Brush Border Membrane
Apical Part Of Cell
Astrocyte Projection
Peroxisome
Peroxisomal Matrix
Cytosol
Molecular Function
Protein Binding
L-amino Acid Transmembrane Transporter Activity
Cystine:glutamate Antiporter Activity
Protein Binding
Palmitoyl-CoA Hydrolase Activity
N-acyltransferase Activity
Transferase Activity, Transferring Acyl Groups
Choloyl-CoA Hydrolase Activity
Acyl-CoA Hydrolase Activity
Glycine N-choloyltransferase Activity
Carboxylic Ester Hydrolase Activity
Medium-chain Acyl-CoA Hydrolase Activity
Long-chain Acyl-CoA Hydrolase Activity
Very Long Chain Acyl-CoA Hydrolase Activity
Myristoyl-CoA Hydrolase Activity
Biological Process
Amino Acid Transmembrane Transport
Glutathione Metabolic Process
Amino Acid Transport
Visual Learning
Response To Toxic Substance
Response To Organic Cyclic Compound
Ventricular System Development
Striatum Development
Adult Behavior
Regulation Of Neutrophil Apoptotic Process
Cellular Response To Oxidative Stress
Glutathione Transmembrane Transport
Response To Nicotine
Regulation Of Cell Population Proliferation
Regulation Of Melanin Biosynthetic Process
Lung Alveolus Development
Modulation Of Chemical Synaptic Transmission
Regulation Of Synapse Organization
Leukocyte Migration
Regulation Of Protein Transport
Response To Redox State
Limb Development
Lens Fiber Cell Differentiation
Platelet Aggregation
Glutamate Homeostasis
L-glutamate Import Across Plasma Membrane
Dipeptide Import Across Plasma Membrane
Regulation Of Cysteine Metabolic Process
Negative Regulation Of Oxidative Stress-induced Neuron Death
Regulation Of Glutathione Biosynthetic Process
Regulation Of AMPA Glutamate Receptor Clustering
Regulation Of Glutamate Metabolic Process
Liver Development
Bile Acid Conjugation
Glycine Metabolic Process
Protein Targeting To Peroxisome
Fatty Acid Metabolic Process
Acyl-CoA Metabolic Process
Bile Acid Biosynthetic Process
Bile Acid Metabolic Process
Taurine Metabolic Process
Animal Organ Regeneration
Pathways
Basigin interactions
Amino acid transport across the plasma membrane
Recycling of bile acids and salts
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Peroxisomal protein import
Peroxisomal protein import
Drugs
Cystine
Glutamic acid
Riluzole
Sulfasalazine
Acetylcysteine
Thimerosal
Glycine
Diseases
Peroxisomal beta-oxidation enzyme deficiency, including: Acyl-CoA oxidase (ACOX) deficiency; D-bifunctional protein (DBP) deficiency; Perrault syndrome; Sterol carrier protein X (SCPx) deficiency; 2-Methylacyl-CoA racemase (AMCR) deficiency; Hypercholanemia
GWAS
Eosinophil counts (
32888494
)
Eosinophil percentage of white cells (
32888494
)
Mood instability (
31168069
)
Neurociticism (
29500382
)
Interacting Genes
6 interacting genes:
BAAT
KRTAP1-1
KRTAP1-3
OTUB1
SLC3A2
TERT
24 interacting genes:
APC
AURKA
BCL10
BUB1
CDKN2A
CTNNA1
DLC1
ERBB2
GOLGA8DP
GOLGA8EP
GOLGA8F
MCC
MLH1
MLH3
MUTYH
ODC1
PDGFRL
PEX5
PTPRJ
RAD54B
RB1
SLC7A11
SMAD4
SRC
Entrez ID
23657
570
HPRD ID
09720
08376
Ensembl ID
ENSG00000151012
ENSG00000136881
Uniprot IDs
Q9UPY5
Q14032
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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