CDC42EP4 and RHOQ

Data Source:
HPRD (in vitro, two hybrid)

		CDC42EP4	RHOQ
Description		CDC42 effector protein 4	ras homolog family member Q
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Adherens Junction Endomembrane System Actin Cytoskeleton Microtubule Cytoskeleton Phagocytic Vesicle	Cytosol Actin Filament Plasma Membrane Golgi-associated Vesicle Membrane Membrane Raft Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding Small GTPase Binding	GTPase Activity Protein Binding Profilin Binding GTP Binding GBD Domain Binding
	Biological Process	Rho Protein Signal Transduction Regulation Of Cell Shape Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Cellular Response To Interferon-gamma	Endocytosis Small GTPase Mediated Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Cell Shape Cell Migration Cell Projection Assembly Cortical Actin Cytoskeleton Organization Cellular Response To Insulin Stimulus Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Transcription By RNA Polymerase II GTP Metabolic Process Positive Regulation Of Glucose Import Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Filopodium Assembly Negative Regulation Of Protein Localization To Plasma Membrane
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Rho GTPase cycle RHO GTPases regulate CFTR trafficking
Drugs
Diseases
GWAS			Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		8 interacting genes: APP CDC42 FAM9B LNX1 RHOQ SRPK2 TGFBR1 WDR6	22 interacting genes: BANP CDC42BPG CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 COPB1 COPG1 DOCK8 EXOC7 GOPC MORN4 NTAQ1 PARD6A PARD6B PFN1 PRKCI RAPGEF1 TRIP10 TRIP6 WASL ZNF417
Entrez ID		23580	23433
HPRD ID		08383	05791
Ensembl ID		ENSG00000179604	ENSG00000119729
Uniprot IDs		B2R6D8 Q9H3Q1	D6W5A7 P17081 V9HWD0
PDB IDs			2ATX
Enriched GO Terms of Interacting Partners?
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