RHOQ and PARD6B

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (in vitro, two hybrid)

		RHOQ	PARD6B
Description		ras homolog family member Q	par-6 family cell polarity regulator beta
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Actin Filament Plasma Membrane Golgi-associated Vesicle Membrane Membrane Raft Extracellular Exosome	Nucleus Cytosol Plasma Membrane Bicellular Tight Junction Cell Cortex Apical Plasma Membrane Protein-containing Complex Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding Profilin Binding GTP Binding GBD Domain Binding	Protein Kinase C Binding Protein Binding
	Biological Process	Endocytosis Small GTPase Mediated Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Cell Shape Cell Migration Cell Projection Assembly Cortical Actin Cytoskeleton Organization Cellular Response To Insulin Stimulus Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Transcription By RNA Polymerase II GTP Metabolic Process Positive Regulation Of Glucose Import Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Filopodium Assembly Negative Regulation Of Protein Localization To Plasma Membrane	Cell-cell Junction Assembly Centrosome Cycle Establishment Or Maintenance Of Cell Polarity Axonogenesis Regulation Of Cell Migration Cell Division Regulation Of Cellular Localization Protein-containing Complex Assembly Bicellular Tight Junction Assembly
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Rho GTPase cycle RHO GTPases regulate CFTR trafficking	Tight junction interactions
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Bipolar disorder ( 21771265)
Interacting Genes		22 interacting genes: BANP CDC42BPG CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 COPB1 COPG1 DOCK8 EXOC7 GOPC MORN4 NTAQ1 PARD6A PARD6B PFN1 PRKCI RAPGEF1 TRIP10 TRIP6 WASL ZNF417	33 interacting genes: APP ARAP3 BANP CDC42 CDCA4 CEP76 FRMD6 GMCL1 GOLGA2 HSF2BP HTRA1 MAGOHB PALS1 PARD3 PARD3B PARD6A PNMA1 PRKCG PRKCI PRKCZ RAC1 RASSF3 RHOJ RHOQ SIAH1 TCP10L3 TRIB3 TRIM35 WDR83 YWHAB YWHAH YWHAZ ZSCAN4
Entrez ID		23433	84612
HPRD ID		05791	18703
Ensembl ID		ENSG00000119729	ENSG00000124171
Uniprot IDs		D6W5A7 P17081 V9HWD0	Q9BYG5
PDB IDs		2ATX
Enriched GO Terms of Interacting Partners?
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