SLC39A14 and BDKRB1

Data Source:
BioGRID (two hybrid)

		SLC39A14	BDKRB1
Description		solute carrier family 39 member 14	bradykinin receptor B1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Early Endosome Membrane Late Endosome Membrane	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection
	Molecular Function	Iron Ion Transmembrane Transporter Activity Manganese Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transporter Activity Cadmium Ion Transmembrane Transporter Activity Ferrous Iron Transmembrane Transporter Activity Anion:cation Symporter Activity	G Protein-coupled Receptor Activity Bradykinin Receptor Activity Protein Binding Peptide Binding
	Biological Process	Chondrocyte Differentiation Gluconeogenesis Cellular Zinc Ion Homeostasis Insulin Receptor Signaling Pathway Regulation Of Hormone Levels Inorganic Anion Transport Cellular Response To Insulin Stimulus Iron Import Into Cell Iron Ion Transmembrane Transport Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Manganese Ion Homeostasis Cadmium Ion Transmembrane Transport Cellular Response To Glucose Stimulus Manganese Ion Transmembrane Transport Zinc Ion Transmembrane Transport Zinc Ion Import Across Plasma Membrane Import Across Plasma Membrane	Negative Regulation Of Protein Phosphorylation Positive Regulation Of Leukocyte Migration Inflammatory Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Response To Mechanical Stimulus Cell Migration Sensory Perception Of Pain Negative Regulation Of Cell Growth Response To Lipopolysaccharide Negative Regulation Of Blood Pressure Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Pathways		Zinc influx into cells by the SLC39 gene family	Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events
Drugs			Ramipril Captopril Zinc Enalaprilat Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio ( 29237677) Verbal declarative memory ( 25648963)	Metabolite levels ( 23823483)
Interacting Genes		3 interacting genes: BDKRB1 LZTS2 SEPTIN3	32 interacting genes: C1orf43 CERS1 DNAJB1 GABBR1 GNAQ GRIN1 HHATL HILPDA HTT INSIG1 LAPTM4B LRRC4C MBOAT7 MDC1 NAGPA NAP1L4 NDFIP1 NF2 OAZ2 RAE1 RETREG1 RTN4 SLC25A28 SLC39A14 SLC44A2 SLC6A8 TMEM42 TMX2 TRAM1L1 TRAT1 UQCRC1 ZNF22
Entrez ID		23516	623
HPRD ID		12288	02639
Ensembl ID		ENSG00000104635	ENSG00000100739
Uniprot IDs		A0A0S2Z534 Q15043	P46663
PDB IDs
Enriched GO Terms of Interacting Partners?
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