ZFYVE26 and TTC23

Data Source:
BioGRID (two hybrid)

		ZFYVE26	TTC23
Description		zinc finger FYVE-type containing 26	tetratricopeptide repeat domain 23
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Centrosome Midbody	Cilium
	Molecular Function	Protein Binding Phosphatidylinositol-3-phosphate Binding Metal Ion Binding	Protein Binding
	Biological Process	Mitotic Cytokinesis Double-strand Break Repair Via Homologous Recombination Regulation Of Cytokinesis	Positive Regulation Of Smoothened Signaling Pathway
Pathways
Drugs
Diseases		Hereditary spastic paraplegia (SPG)
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Asthma ( 31959851) Asthma (childhood onset) ( 31036433)
Interacting Genes		35 interacting genes: ALAS1 ASB15 CBY2 CCDC125 CCDC136 CEP44 GOLGA2 GPRASP2 HMBOX1 HNRNPC HOOK2 KRT15 KRT27 KRT34 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 MAGED1 MDFI PLEKHF2 PNMA1 PNMA5 PPP1R16A PRDM6 SPAG5 SSX2IP TADA2A TCEANC TDO2 TFIP11 TRAF1 TTC23 USHBP1 USP20	99 interacting genes: ABI1 ADCY4 ALAS1 APP BANP BHLHE40 BLZF1 C1orf109 CBX8 CCDC102B CCDC24 CCNDBP1 CDK18 CDR2 CNTROB CREBZF CYSRT1 DISC1 EFCAB3 FAM161B FSD2 GOLGA2 GOLGA6L9 GPANK1 GPRASP2 GRIPAP1 HOOK2 HSF2BP HTT INSC IQCE KASH5 KDM1A KIAA1328 KLHL42 KRT15 KRT16 KRT27 KRT31 KRT34 KRT36 KRT40 KRTAP10-3 KRTAP10-8 LCN2 LDOC1 LZTS2 MAGED1 MBD3 MDFI MED12L MESD MID2 MKRN3 MTUS2 NOTO NUTM1 PICK1 PIH1D2 PLEKHG4 PNMA1 PNMA5 POLR2J3 POU6F2 PPP1R16A PRDM6 PRKAB2 PRPH PSORS1C2 RAD51D RBCK1 SPAG11B SPAG5 SPAG8 SPDEF SSX2IP TADA2A TEX13A TLE5 TRAF2 TRAPPC6A TRIB3 TRIM10 TRIM32 TRIM54 TRIM73 TRIP6 TSGA10IP UBXN11 USHBP1 XIAP XRN2 ZBED1 ZBTB16 ZBTB42 ZDHHC17 ZFHX3 ZFYVE26 ZIM2
Entrez ID		23503	64927
HPRD ID		15734	07777
Ensembl ID		ENSG00000072121	ENSG00000103852
Uniprot IDs		Q68DK2	Q5W5X9
PDB IDs
Enriched GO Terms of Interacting Partners?
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