TTC23 and PRPH

Data Source:
BioGRID (two hybrid)

		TTC23	PRPH
Description		tetratricopeptide repeat domain 23	peripherin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cilium	Cytoplasm Intermediate Filament Membrane Axon Perikaryon Type III Intermediate Filament Extracellular Exosome
	Molecular Function	Protein Binding	Structural Molecule Activity Protein Binding
	Biological Process	Positive Regulation Of Smoothened Signaling Pathway	Intermediate Filament Cytoskeleton Organization
Pathways
Drugs
Diseases			Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
GWAS			Prostate cancer ( 21743467) Sural nerve amplitude potential ( 30992453)
Interacting Genes		99 interacting genes: ABI1 ADCY4 ALAS1 APP BANP BHLHE40 BLZF1 C1orf109 CBX8 CCDC102B CCDC24 CCNDBP1 CDK18 CDR2 CNTROB CREBZF CYSRT1 DISC1 EFCAB3 FAM161B FSD2 GOLGA2 GOLGA6L9 GPANK1 GPRASP2 GRIPAP1 HOOK2 HSF2BP HTT INSC IQCE KASH5 KDM1A KIAA1328 KLHL42 KRT15 KRT16 KRT27 KRT31 KRT34 KRT36 KRT40 KRTAP10-3 KRTAP10-8 LCN2 LDOC1 LZTS2 MAGED1 MBD3 MDFI MED12L MESD MID2 MKRN3 MTUS2 NOTO NUTM1 PICK1 PIH1D2 PLEKHG4 PNMA1 PNMA5 POLR2J3 POU6F2 PPP1R16A PRDM6 PRKAB2 PRPH PSORS1C2 RAD51D RBCK1 SPAG11B SPAG5 SPAG8 SPDEF SSX2IP TADA2A TEX13A TLE5 TRAF2 TRAPPC6A TRIB3 TRIM10 TRIM32 TRIM54 TRIM73 TRIP6 TSGA10IP UBXN11 USHBP1 XIAP XRN2 ZBED1 ZBTB16 ZBTB42 ZDHHC17 ZFHX3 ZFYVE26 ZIM2	36 interacting genes: CDC37 CT55 DDX6 DES FCHO1 INCA1 KIFC3 KRT14 KRT15 KRT16 KRT19 KRT20 KRT24 KRT27 KRT31 KRT75 LCA5L LENG1 LMNB1 LNX1 MAGOHB MYO5A NXF1 PIAS2 PPP1R13B PPP1R18 PRKAA2 PRPH2 PSMA1 TCEA2 TCP10L TTC23 VIM ZC4H2 ZMAT2 ZNF572
Entrez ID		64927	5630
HPRD ID		07777	01365
Ensembl ID		ENSG00000103852	ENSG00000135406
Uniprot IDs		Q5W5X9	B3KWQ6 P41219
PDB IDs
Enriched GO Terms of Interacting Partners?
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