NOMO1 and TOM1L1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NOMO1	TOM1L1
Description		NODAL modulator 1	target of myb1 like 1 membrane trafficking protein
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Cytoplasm Lysosome Endosome Golgi Stack Cytosol Endosome Membrane Membrane Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding Carbohydrate Binding	Protein Binding SH3 Domain Binding Protein Kinase Binding Clathrin Binding Protein Kinase Activator Activity Ubiquitin Binding
	Biological Process	Biological_process Negative Regulation Of Nodal Signaling Pathway	Intracellular Protein Transport Signal Transduction Positive Regulation Of Protein Autophosphorylation Activation Of Protein Kinase Activity Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Mitotic Nuclear Division Regulation Of DNA Biosynthetic Process
Pathways
Drugs		Theophylline
Diseases
GWAS			Carotid intima media thickness x smoking interaction ( 32117412) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Photic sneeze reflex ( 27182965) Urinary albumin-to-creatinine ratio ( 32600054)
Interacting Genes		12 interacting genes: ATF7IP BAG6 ECT2 EXOSC10 NCLN SHBG STAT1 TOM1L1 TRIM55 TRIM63 UBQLN4 UPF2	29 interacting genes: AMFR CCDC47 CELF1 COPS7A CWF19L1 DNAJB13 FYN GLUD2 GRB2 GSN HGS HNRNPH1 MAP3K3 NDC80 NOMO1 PDPN PELP1 PHYH PIK3R1 PWP2 RAB18 TASOR TOLLIP TSG101 TUBA1B UBC UBXN4 VAV2 VCP
Entrez ID		23420	10040
HPRD ID		11398	05266
Ensembl ID		ENSG00000103512	ENSG00000141198
Uniprot IDs		Q15155	O75674 Q8NI65
PDB IDs			3RRU
Enriched GO Terms of Interacting Partners?
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