PUM2 and MED23

Data Source:
HPRD (two hybrid)

		PUM2	MED23
Description		pumilio RNA binding family member 2	mediator complex subunit 23
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GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoplasmic Stress Granule Nuclear Membrane Perinuclear Region Of Cytoplasm	Nucleoplasm Transcription Regulator Complex Mediator Complex
	Molecular Function	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding MiRNA Binding	Transcription Coactivator Activity Protein Binding
	Biological Process	Regulation Of Translation Posttranscriptional Regulation Of Gene Expression Stress Granule Assembly Production Of MiRNAs Involved In Gene Silencing By MiRNA Regulation Of MRNA Stability Regulation Of Chromosome Segregation Regulation Of Gene Silencing By MiRNA Positive Regulation Of RIG-I Signaling Pathway Positive Regulation Of Gene Silencing By MiRNA	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated
Pathways		Neddylation	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Body mass index ( 28892062) Low density lipoprotein cholesterol levels ( 32154731)	L-arginine levels ( 25245031) Type 2 diabetes ( 30054458)
Interacting Genes		24 interacting genes: AURKA DAZ1 DAZ3 DAZ4 DAZL MED23 MED4 MIR128-2 MIR17 MIR199A1 MIR199A2 MIR214 MIR221 MIR7-1 MIR92A2 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G NANOS1	15 interacting genes: CEBPB CTDP1 ELF3 ESR1 ESR2 ETS1 FOXJ3 MED13 MED9 NCOA6 PUM2 RELA SREBF1 VDR WDTC1
Entrez ID		23369	9439
HPRD ID		09527	05436
Ensembl ID		ENSG00000055917	ENSG00000112282
Uniprot IDs		A0A0A0MR59 B7ZL34 Q8TB72	Q05DL5 Q9ULK4
PDB IDs		3Q0Q 3Q0R 3Q0S	6H02
Enriched GO Terms of Interacting Partners?
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