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PLOD3

Description procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
Image
GO Annotations Cellular Component
  • Extracellular Space
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Lumen
  • Endoplasmic Reticulum Membrane
  • Rough Endoplasmic Reticulum
  • Golgi Apparatus
  • Trans-Golgi Network
  • Collagen-containing Extracellular Matrix
  • Extracellular Exosome
Molecular Function
  • Iron Ion Binding
  • Protein Binding
  • Procollagen-lysine 5-dioxygenase Activity
  • L-ascorbic Acid Binding
  • Procollagen Glucosyltransferase Activity
  • Procollagen Galactosyltransferase Activity
Biological Process
  • In Utero Embryonic Development
  • Endothelial Cell Morphogenesis
  • Protein O-linked Glycosylation
  • Protein Localization
  • Peptidyl-lysine Hydroxylation
  • Protein Phosphopantetheinylation
  • Neural Tube Development
  • Collagen Fibril Organization
  • Cellular Response To Hormone Stimulus
  • Collagen Metabolic Process
  • Vasodilation
  • Hydroxylysine Biosynthetic Process
  • Epidermis Morphogenesis
  • Lung Morphogenesis
  • Basement Membrane Assembly
Pathways
  • Collagen biosynthesis and modifying enzymes
Drugs
  • Ascorbic acid
Diseases
GWAS
  • Blood protein levels ( 30072576)
Interacting Genes 20 interacting genes: CCDC85B COIL COL17A1 CRIP3 DPPA2 EFHC2 EHMT2 FAM153A IP6K2 KCTD9 KHNYN L3MBTL3 LINC00839 NAB2 RAB3IP RALY RHOU RHOXF2 SORBS3 ZNF620
Entrez ID 8985
HPRD ID 04347
Ensembl ID ENSG00000106397
Uniprot IDs O60568 Q9UG85
PDB IDs 6FXK 6FXM 6FXR 6FXT 6FXX 6FXY
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025