ARPC1A

Description		actin related protein 2/3 complex subunit 1A
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GO Annotations	Cellular Component	Nucleus Cytosol Arp2/3 Protein Complex Actin Cytoskeleton Site Of Double-strand Break Extracellular Exosome
	Molecular Function	Actin Binding Actin Filament Binding
	Biological Process	Actin Cytoskeleton Organization Arp2/3 Complex-mediated Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Ephrin Receptor Signaling Pathway Membrane Organization
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Alcohol consumption ( 31358974) Dehydroepiandrosterone sulphate levels ( 21533175) Facial emotion recognition (sad faces) ( 28608620) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Medication use (calcium channel blockers) ( 31015401) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Serum metabolite levels ( 23093944) Ticagrelor levels in individuals with acute coronary syndromes treated with ticagrelor ( 25935875)
Interacting Genes		2 interacting genes: ERCC6 EXOC7
Entrez ID		10552
HPRD ID		07252
Ensembl ID		ENSG00000241685
Uniprot IDs		Q92747 V9HVZ6
PDB IDs		6YW7
Enriched GO Terms of Interacting Partners?
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