PMPCA and ASS1

Data Source:
BioGRID (biochemical)

		PMPCA	ASS1
Description		peptidase, mitochondrial processing subunit alpha	argininosuccinate synthase 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix	Nucleus Cytoplasm Mitochondrial Outer Membrane Lysosome Endoplasmic Reticulum Cytosol Perikaryon Extracellular Exosome Cell Body Fiber
	Molecular Function	Protein Binding Metal Ion Binding	RNA Binding Argininosuccinate Synthase Activity Protein Binding ATP Binding Toxic Substance Binding Amino Acid Binding Identical Protein Binding
	Biological Process	Protein Processing Involved In Protein Targeting To Mitochondrion Mitochondrial Calcium Ion Transmembrane Transport	Urea Cycle Citrulline Metabolic Process Argininosuccinate Metabolic Process Kidney Development Liver Development Arginine Biosynthetic Process Aspartate Metabolic Process Acute-phase Response Midgut Development Aging Response To Nutrient Circadian Rhythm Response To Zinc Ion Response To Mycotoxin Response To Estradiol Response To Drug Positive Regulation Of Nitric Oxide Biosynthetic Process Response To Growth Hormone Diaphragm Development Cellular Response To Lipopolysaccharide Cellular Response To Amino Acid Stimulus Cellular Response To Ammonium Ion Cellular Response To CAMP Cellular Response To Interferon-gamma Cellular Response To Tumor Necrosis Factor Cellular Response To Glucagon Stimulus Cellular Response To Oleic Acid Cellular Response To Amine Stimulus Cellular Response To Laminar Fluid Shear Stress Cellular Response To Dexamethasone Stimulus Negative Regulation Of Leukocyte Cell-cell Adhesion
Pathways		Mitochondrial protein import Processing of SMDT1	Urea cycle
Drugs			Arginine Aspartic acid Aspartic acid Citrulline Citrulline ATP
Diseases			Citrullinemia (CTLN)
GWAS		Apolipoprotein B levels ( 32203549) Chronotype ( 30696823) Crohn's disease ( 28067908) Granulocyte count ( 27863252) Inflammatory bowel disease ( 28067908 23128233) Joint damage in rheumatoid arthritis ( 26498133) LDL cholesterol levels ( 32203549) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Serum total protein level ( 29403010) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Ulcerative colitis ( 28067908) White blood cell count ( 27863252)
Interacting Genes		5 interacting genes: BMPR2 LINC01554 PMPCB SKIV2L ZNF76	15 interacting genes: AKTIP APP ARAF ASCC2 ELN JAK2 LINC01554 MLH1 MT2A PTPN1 SLC13A1 SUMO2 TERF1 TERF2 USP4
Entrez ID		23203	445
HPRD ID		07500	04590
Ensembl ID		ENSG00000165688	ENSG00000130707
Uniprot IDs		Q10713	P00966 Q5T6L4
PDB IDs			2NZ2
Enriched GO Terms of Interacting Partners?
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