EPB41L3 and CEP152

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EPB41L3	CEP152
Description		erythrocyte membrane protein band 4.1 like 3	centrosomal protein 152
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GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Cell-cell Junction Cell Junction Axolemma Paranode Region Of Axon Juxtaparanode Region Of Axon	Pericentriolar Material Nucleoplasm Centrosome Centriole Cytosol Deuterosome
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Protein-membrane Anchor Activity	Protein Binding Protein Kinase Binding
	Biological Process	Regulation Of Cell Growth Protein Localization To Paranode Region Of Axon Apoptotic Process Biological_process Regulation Of Cell Shape Cortical Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Paranodal Junction Assembly Actomyosin Structure Organization Myelin Maintenance Neuron Projection Morphogenesis Protein Localization To Juxtaparanode Region Of Axon Protein Localization To Plasma Membrane	G2/M Transition Of Mitotic Cell Cycle Centriole Replication Regulation Of G2/M Transition Of Mitotic Cell Cycle Centrosome Duplication Ciliary Basal Body-plasma Membrane Docking De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation
Pathways		Neurexins and neuroligins	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases			Seckel syndrome
GWAS		Cerebral amyloid deposition (PET imaging) ( 26252872) Chronic kidney disease ( 31152163) Diverticular disease ( 30177863) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Glomerular filtration rate (creatinine) ( 28452372) Optic nerve head parameters (multi-trait analysis) ( 31798171) Sleep duration ( 25469926) Social communication problems ( 24564958) Thyroid nodules ( 30099483) Vertical cup-disc ratio ( 31798171)	Diastolic blood pressure ( 30578418) Insomnia ( 23728906) Obesity-related traits ( 23251661)
Interacting Genes		19 interacting genes: ATXN1L CADM1 CEP152 CLNS1A CNTNAP2 HSPB1 IGSF21 MBIP PAXIP1 PSEN1 SPANXN2 SPTBN1 TCF4 UNC13A YWHAB YWHAG YWHAH YWHAQ YWHAZ	1 interacting genes: EPB41L3
Entrez ID		23136	22995
HPRD ID		05622	16778
Ensembl ID		ENSG00000082397	ENSG00000103995
Uniprot IDs		A0A0A0MRA8 A8K968 Q9Y2J2	O94986 Q3B7A2
PDB IDs		2HE7 3BIN 6IBE	4N7V 6CSU 6CSV
Enriched GO Terms of Interacting Partners?
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