CEP152 and EPB41L3

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CEP152	EPB41L3
Description		centrosomal protein 152	erythrocyte membrane protein band 4.1 like 3
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GO Annotations	Cellular Component	Pericentriolar Material Nucleoplasm Centrosome Centriole Cytosol Deuterosome	Cytosol Cytoskeleton Plasma Membrane Cell-cell Junction Cell Junction Axolemma Paranode Region Of Axon Juxtaparanode Region Of Axon
	Molecular Function	Protein Binding Protein Kinase Binding	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Protein-membrane Anchor Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Centriole Replication Regulation Of G2/M Transition Of Mitotic Cell Cycle Centrosome Duplication Ciliary Basal Body-plasma Membrane Docking De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation	Regulation Of Cell Growth Protein Localization To Paranode Region Of Axon Apoptotic Process Biological_process Regulation Of Cell Shape Cortical Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Paranodal Junction Assembly Actomyosin Structure Organization Myelin Maintenance Neuron Projection Morphogenesis Protein Localization To Juxtaparanode Region Of Axon Protein Localization To Plasma Membrane
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	Neurexins and neuroligins
Drugs
Diseases		Seckel syndrome
GWAS		Diastolic blood pressure ( 30578418) Insomnia ( 23728906) Obesity-related traits ( 23251661)	Cerebral amyloid deposition (PET imaging) ( 26252872) Chronic kidney disease ( 31152163) Diverticular disease ( 30177863) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Glomerular filtration rate (creatinine) ( 28452372) Optic nerve head parameters (multi-trait analysis) ( 31798171) Sleep duration ( 25469926) Social communication problems ( 24564958) Thyroid nodules ( 30099483) Vertical cup-disc ratio ( 31798171)
Interacting Genes		1 interacting genes: EPB41L3	19 interacting genes: ATXN1L CADM1 CEP152 CLNS1A CNTNAP2 HSPB1 IGSF21 MBIP PAXIP1 PSEN1 SPANXN2 SPTBN1 TCF4 UNC13A YWHAB YWHAG YWHAH YWHAQ YWHAZ
Entrez ID		22995	23136
HPRD ID		16778	05622
Ensembl ID		ENSG00000103995	ENSG00000082397
Uniprot IDs		O94986 Q3B7A2	A0A0A0MRA8 A8K968 Q9Y2J2
PDB IDs		4N7V 6CSU 6CSV	2HE7 3BIN 6IBE
Enriched GO Terms of Interacting Partners?
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