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TAB2 and VIM
Data Source:
BioGRID
(two hybrid)
TAB2
VIM
Description
TGF-beta activated kinase 1 (MAP3K7) binding protein 2
vimentin
Image
GO Annotations
Cellular Component
Nucleoplasm
Cytosol
Plasma Membrane
Endosome Membrane
Cytoplasm
Peroxisome
Cytosol
Polysome
Cytoskeleton
Intermediate Filament
Plasma Membrane
Focal Adhesion
Nuclear Matrix
Cell Leading Edge
Neuron Projection
Intermediate Filament Cytoskeleton
Phagocytic Vesicle
Extracellular Exosome
Ribonucleoprotein Complex
Molecular Function
Protein Binding
Ubiquitin Binding
Metal Ion Binding
K63-linked Polyubiquitin Modification-dependent Protein Binding
Double-stranded RNA Binding
Structural Constituent Of Cytoskeleton
Structural Constituent Of Eye Lens
Protein Binding
Protein Domain Specific Binding
Identical Protein Binding
Scaffold Protein Binding
Keratin Filament Binding
Biological Process
Activation Of MAPK Activity
Stimulatory C-type Lectin Receptor Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
I-kappaB Kinase/NF-kappaB Signaling
JNK Cascade
Heart Development
Negative Regulation Of Autophagy
Response To Lipopolysaccharide
Fc-epsilon Receptor Signaling Pathway
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Protein Kinase Activity
T Cell Receptor Signaling Pathway
Positive Regulation Of NF-kappaB Transcription Factor Activity
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Interleukin-1-mediated Signaling Pathway
Negative Regulation Of Neuron Projection Development
Astrocyte Development
Viral Process
Cytokine-mediated Signaling Pathway
Muscle Filament Sliding
Positive Regulation Of Collagen Biosynthetic Process
Regulation Of MRNA Stability
Intermediate Filament Organization
Positive Regulation Of Translation
Bergmann Glial Cell Differentiation
SMAD Protein Signal Transduction
Lens Fiber Cell Development
Cellular Response To Lipopolysaccharide
Cellular Response To Muramyl Dipeptide
Cellular Response To Interferon-gamma
Pathways
Nuclear signaling by ERBB4
Nuclear signaling by ERBB4
NOD1/2 Signaling Pathway
Downstream TCR signaling
FCERI mediated NF-kB activation
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
activated TAK1 mediates p38 MAPK activation
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
TNFR1-induced NFkappaB signaling pathway
CLEC7A (Dectin-1) signaling
TICAM1,TRAF6-dependent induction of TAK1 complex
Interleukin-1 signaling
IRAK2 mediated activation of TAK1 complex
TRAF6-mediated induction of TAK1 complex within TLR4 complex
Alpha-protein kinase 1 signaling pathway
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
Caspase-mediated cleavage of cytoskeletal proteins
Striated Muscle Contraction
Interleukin-4 and Interleukin-13 signaling
Chaperone Mediated Autophagy
Late endosomal microautophagy
Aggrephagy
Drugs
Artenimol
Phenethyl Isothiocyanate
Diseases
GWAS
Breast cancer (
22383897
29059683
)
Coronary artery disease (
33020668
)
Diverticulitis (
28585551
)
Dupuytren's disease (
28886342
21732829
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Cholesterol, total (
24097068
)
HDL cholesterol levels (
32203549
)
Mean spheric corpuscular volume (
32888494
)
Total cholesterol levels (
28334899
)
Triglyceride levels (
32203549
)
Interacting Genes
43 interacting genes:
APP
CAMK2A
CST9L
EIF2AK2
EMILIN1
ERBB4
FN1
FOSL1
GTF2I
HDAC1
HDAC3
HDAC5
HSF2BP
IKBKB
IKBKG
IRAK1
KRT85
MAP3K7
NCOR1
NFKB1
NR2C2
NUMBL
PPIL3
PPP2CB
SLC19A3
TAB1
TBL1X
TGM2
TNFRSF11A
TPM3
TRAF2
TRAF3IP1
TRAF6
TTN
UBC
UBE2I
VIM
VPS52
XIAP
YWHAZ
ZBTB16
ZFP64
ZNF143
171 interacting genes:
ABLIM1
AKT1
ANKRD35
ANXA7
APIP
APLP1
APP
ARMC7
ARMCX2
ATN1
BFSP1
BHLHE40
BRD1
BYSL
C2CD6
CAMK2D
CAPN1
CASP3
CASP6
CASP7
CASP8
CASP9
CBX8
CCDC187
CDH5
CDK1
CDKN1A
CEP126
CHD3
COPS6
CRCT1
CREB1
CRMP1
CT55
CWF19L2
DCTN1
DEFB1
DES
DIS3L2
DNM1L
DPPA4
DSP
DUX4
DYNLL1
ENTR1
ESS2
FABP4
FAM107A
FAM118B
FAM161A
FUBP1
GADD45A
GEM
GFAP
GOPC
GRB2
GSK3B
HABP4
HAP1
HMG20B
HSPB1
HTRA2
ING5
IP6K1
ITGB4
IVNS1ABP
KARS1
KAT7
KIAA0408
KIF15
KIF9
KIFC3
KRT20
KRT75
LGALS14
LINC01554
LORICRIN
LRIF1
MAFG
MAN2A2
MCPH1
MEN1
MICAL1
MRPL44
MTDH
NEFL
NEFM
NFATC2
NFKBID
NIF3L1
NME2
NOC4L
NR1H2
NUP85
OSBP2
PAK2
PDLIM1
PIAS4
PKD1
PKN1
PKP1
PLA2G2A
PLA2G4A
PLEC
PNMA5
POLR1C
PPHLN1
PPL
PPP1R18
PRKACA
PRPH
PSMA1
PSMC5
PSMD7
PSME1
PUF60
RAB8B
RABAC1
RAD51
RBM48
RIBC2
ROCK1
RPA1
SCNM1
SERBP1
SETDB1
SH3GL1
SH3GL3
SH3YL1
SIRPA
SIRT6
SLC25A6
SLC27A6
SMAD3
SMARCB1
SRRT
STK19
STX1A
SUMO2
SUMO3
SYN1
TAB2
TCEA2
TCHP
TLE5
TNFRSF14
TNNT1
TRIM14
TRIM15
TRIM28
TRIM29
TRIOBP
TSC22D1
TTR
TUBA1C
TUBGCP4
TXLNB
TXN
TXN2
UPP1
UPP2
UROD
UTP14A
WBP11
XRCC4
YAE1
YWHAE
YWHAZ
ZHX1
ZNF384
ZNF572
Entrez ID
23118
7431
HPRD ID
05483
01899
Ensembl ID
ENSG00000055208
ENSG00000026025
Uniprot IDs
B4DIR9
Q9NYJ8
P08670
V9HWE1
PDB IDs
2DAE
2WWZ
2WX0
2WX1
1GK4
1GK6
1GK7
3G1E
3KLT
3S4R
3SSU
3SWK
3TRT
3UF1
4MCY
4MCZ
4MD0
4MD5
4MDI
4MDJ
4YPC
4YV3
5WHF
6ATF
6ATI
6BIR
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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