MRPS27 and NECAB2

Data Source:
BioGRID (two hybrid)

		MRPS27	NECAB2
Description		mitochondrial ribosomal protein S27	N-terminal EF-hand calcium binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Small Ribosomal Subunit	Cytoplasm Plasma Membrane Axon Dendrite
	Molecular Function	TRNA Binding Protein Binding RRNA Binding Mitochondrial Ribosome Binding	Calcium Ion Binding Protein Binding A2A Adenosine Receptor Binding Type 5 Metabotropic Glutamate Receptor Binding
	Biological Process	Cell Population Proliferation Mitochondrial Translational Elongation Mitochondrial Translational Termination Positive Regulation Of Mitochondrial Translation	Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Adenosine Receptor Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Glutamate Receptor Signaling Pathway Negative Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Protein Localization To Membrane
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Body mass index (change over time) ( 25378290) Corneal astigmatism ( 29422769) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Rheumatoid arthritis ( 30891314)
Interacting Genes		3 interacting genes: NECAB2 PTEN YWHAQ	89 interacting genes: ADORA2A AIMP2 BEX2 BEX3 BYSL C19orf25 C1orf109 C1orf216 CAGE1 CAPN3 CARD9 CCDC121 CCDC146 CCDC153 CCDC33 CCNK CDC37 CENPO CPEB2 DAXX DFFA DGCR6 DGCR6L DTNBP1 DYNC1I2 EAF2 EHHADH EIF4E2 EMILIN1 FAM161A FAM161B FANCG FXR2 GCC1 GOLGA2 GTPBP10 HAUS1 INPP1 INTS10 ISCU KANK2 KANSL1 KDM1A KIFC3 KLC3 KLC4 KPNA2 LENG1 LNX1 MED14 MRPS27 MSGN1 MTMR9 MYO15B MYPOP NECAB1 NEK6 NIP7 NOC4L NTAQ1 ODAD3 ODAD4 OIP5 PATJ PCM1 PICK1 POLR2C PRKAA2 PRPF18 PSMA1 PUS10 RCOR3 RIC8A RUNX1T1 SDCBP SH2D4A SMARCD1 SNAPIN SOGA1 SSC5D TCEA2 TEX11 TRIM59 TRIML2 TTR USHBP1 USP7 VTA1 ZNF655
Entrez ID		23107	54550
HPRD ID		17596	13263
Ensembl ID		ENSG00000113048	ENSG00000103154
Uniprot IDs		A0A024RAJ1 G5EA06 Q6PKB3 Q92552	Q7Z6G3
PDB IDs		3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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