SNW1 and GRIPAP1

Data Source:
BioGRID (two hybrid)

		SNW1	GRIPAP1
Description		SNW domain containing 1	GRIP1 associated protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cyclin/CDK Positive Transcription Elongation Factor Complex Nuclear Matrix Nuclear Body Nuclear Speck U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Nucleoplasm Cytosol Axon Dendrite Intracellular Membrane-bounded Organelle Recycling Endosome Membrane Blood Microparticle Postsynaptic Recycling Endosome Glutamatergic Synapse Extrinsic Component Of Postsynaptic Early Endosome Membrane
	Molecular Function	Transcription Coactivator Activity Transcription Corepressor Activity RNA Binding Notch Binding Protein Binding Enzyme Binding Nuclear Hormone Receptor Binding Vitamin D Receptor Binding Retinoic Acid Receptor Binding SMAD Binding Androgen Receptor Binding	Molecular_function Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II MRNA Splicing, Via Spliceosome Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Notch Signaling Pathway Positive Regulation Of Transcription Of Notch Receptor Target Viral Process Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation By Host Of Viral Transcription Positive Regulation Of Notch Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of MRNA Splicing, Via Spliceosome Retinoic Acid Receptor Signaling Pathway Regulation Of Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Neurogenesis Positive Regulation Of Histone H3-K4 Methylation Regulation Of Vitamin D Receptor Signaling Pathway Positive Regulation Of Vitamin D Receptor Signaling Pathway Cellular Response To Retinoic Acid	Biological_process Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Regulation Of Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Regulation Of Recycling Endosome Localization Within Postsynapse Regulation Of Modification Of Synaptic Structure
Pathways		Pre-NOTCH Transcription and Translation Pre-NOTCH Transcription and Translation Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells NOTCH1 Intracellular Domain Regulates Transcription NOTCH1 Intracellular Domain Regulates Transcription SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Notch-HLH transcription pathway mRNA Splicing - Major Pathway RUNX3 regulates NOTCH signaling RUNX3 regulates NOTCH signaling NOTCH3 Intracellular Domain Regulates Transcription NOTCH3 Intracellular Domain Regulates Transcription NOTCH4 Intracellular Domain Regulates Transcription
Drugs
Diseases
GWAS		Response to platinum-based chemotherapy in non-small-cell lung cancer ( 22872573)	Eosinophil percentage of white cells ( 32888494)
Interacting Genes		97 interacting genes: ABLIM3 ACTN2 ASCC2 BICD2 BYSL C1orf216 CCDC125 CEP55 CEP70 CIR1 CWF19L2 DAXX EP300 ERCC3 EXOSC5 FAM90A1 GABPB1 GAS2L2 GOLGA2 GRIPAP1 HDAC2 HMBOX1 HOOK2 HSF2BP IKBKG IKZF1 JDP2 KANK2 KRT40 LRP2BP LZTS2 MAGEA1 MAGOHB MAPK6 MCMBP MEN1 MFAP1 MISP MSL1 MTUS2 NCK2 NCOA1 NCOR1 NCOR2 NOTCH1 NOTCH3 NR0B1 NR0B2 NXF1 OCLN ODF2 OSTF1 PABPN1 PCBD2 PGR PICK1 PPIL1 PRKAA2 PRKAR1B RABEP1 RARA RB1 RBL1 RBL2 RBPJ RINT1 RXRA SAAL1 SART1 SIN3A SIRT1 SKI SMAD2 SMAD3 SMAD4 SNRNP200 SNU13 SPECC1L STEEP1 SUMO2 TCP11L1 TEX11 TFIP11 TNNT1 TOP1 TRAF1 TRIM15 TRIM23 TRIM55 TRIM63 TTC14 USF1 VAV2 VDR VPS39 WBP4 ZSCAN1	69 interacting genes: AARD ANKRD11 ARL15 ATG5 BYSL CASP3 CBX8 CCDC103 CCDC185 CCDC187 CCNH CCNT1 CDC37 CEP57L1 CFAP53 CWF19L2 DAXX DISC1 DUSP26 EHHADH ELOA ENKD1 FAM161A FAM50B FAM90A1 GAS8 GRIA1 GRIP1 GRM7 HDAC4 HSPB1 ING4 ING5 LNX1 MAP3K1 MEOX2 MFAP1 MLLT6 NUAK2 PIBF1 PKP2 PPP1R18 PRPF18 PSMB1 RAB4A RCOR3 SMAD2 SMARCE1 SMURF1 SNAPC5 SNW1 SPP1 STAP1 TBC1D30 TCEA2 TCP10L TEPSIN TES TRAF2 TSGA10IP TSHZ2 TSNAX TTC23 USP2 ZMAT2 ZNF219 ZNF250 ZNF35 ZNF835
Entrez ID		22938	56850
HPRD ID		04340	02325
Ensembl ID		ENSG00000100603	ENSG00000068400
Uniprot IDs		G3V3A4 Q13573	Q4V328
PDB IDs		5MQF 5XJC 5YZG 5Z58 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM 7A5P
Enriched GO Terms of Interacting Partners?
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