DZIP1 and PPP1R18

Data Source:
BioGRID (two hybrid)

		DZIP1	PPP1R18
Description		DAZ interacting zinc finger protein 1	protein phosphatase 1 regulatory subunit 18
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centriole Cytosol Centriolar Satellite Ciliary Basal Body Ciliary Transition Fiber	Cytoplasm Cytoskeleton
	Molecular Function	Protein Binding Metal Ion Binding	Actin Binding Protein Binding Phosphatase Binding
	Biological Process	Smoothened Signaling Pathway Multicellular Organism Development Germ Cell Development Spermatogenesis Regulation Of Protein Binding Establishment Of Protein Localization Positive Regulation Of Cilium Assembly Cytoplasmic Sequestering Of Protein Cilium Assembly Protein Localization To Cilium
Pathways		Hedgehog 'on' state
Drugs
Diseases
GWAS		Glomerular filtration rate (cystatin C) ( 26831199) Response to statins (LDL cholesterol change) ( 25350695)	Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Hemoglobin levels ( 32327693) Lung cancer ( 28604730)
Interacting Genes		9 interacting genes: DAZ1 DAZ4 LUC7L2 MOS OPTN PPP1R18 PPP2R5A PRPF40A TNS2	80 interacting genes: ABRA ACTN3 BICD2 CALCOCO2 CARD9 CBY2 CCDC102B CCDC136 CCDC57 CCDC88B CDR2L CEP70 COG6 DES DZIP1 EIF3L FAM9B FHL5 FSD2 GCC1 GFAP GMCL1 GOLGA2 GOLGA6L9 GOPC GRIPAP1 GTPBP3 HAP1 HOMER3 HOOK2 HSF2BP IKZF3 KASH5 KCTD9 KRT13 KRT15 KRT16 KRT19 KRT27 KRT31 KRT33B KRT34 KRT36 KRT40 LDOC1 LZTS1 LZTS2 MAD1L1 MAPK1 MEOX2 MID2 MRPL38 MTUS2 NACA NEFL PDE4DIP PIBF1 PLEKHF2 PPP1CA PPP1CC PPP1R13B PRPH SORBS3 SPDL1 STX11 TCF4 TEX11 TFIP11 TRAF2 TRIM23 TRIM27 TRIM54 TRIM62 TRIM69 TSC1 TSGA10 VIM VPS52 ZMYND12 ZRANB1
Entrez ID		22873	170954
HPRD ID		16363	11172
Ensembl ID		ENSG00000134874	ENSG00000146112
Uniprot IDs		B3KSP1 Q86YF9	A0A024RCJ8 Q6NYC8
PDB IDs
Enriched GO Terms of Interacting Partners?
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