ADGRL1 and ANKS1A

Data Source:
HPRD (two hybrid)

		ADGRL1	ANKS1A
Description		adhesion G protein-coupled receptor L1	ankyrin repeat and sterile alpha motif domain containing 1A
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Postsynaptic Density Integral Component Of Membrane Axon Growth Cone Presynaptic Membrane Neuron Projection Synapse	Nucleoplasm Cytosol Neuron Projection
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Latrotoxin Receptor Activity Carbohydrate Binding Cell Adhesion Molecule Binding	Protein Binding Ephrin Receptor Binding
	Biological Process	Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of Synapse Maturation	Substrate-dependent Cell Migration Neuron Remodeling Ephrin Receptor Signaling Pathway Regulation Of Ephrin Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 24262325) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary heart disease ( 21378990) Height ( 28552196 23563607 18391951) Mean platelet volume ( 32888494) Non-small cell lung cancer ( 23144319) Obesity-related traits ( 23251661) Platelet distribution width ( 32888494) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for body mass index ( 25673412)
Interacting Genes		9 interacting genes: ANKS1A APC CACNA1A DLG3 DLG4 PSMA3 ROS1 SHANK1 SHANK2	99 interacting genes: ABI2 ADGRL1 ALDOC ANKRD55 ARAP3 ARHGAP10 BCAR1 BLZF1 C17orf50 C19orf54 C22orf39 C3orf36 C9orf152 CADPS CCDC184 CCDC33 CHCHD3 CYSRT1 DAB2IP DOK3 EGFR ERBB2 ERBB4 ESM1 FAM217B FAM221A FAM86C1P FCHSD2 FHL5 GOLGA2 GPRIN2 HOXA1 HOXC8 ID3 IKZF3 ISCA2 ITIH6 KCTD9 KEAP1 KIAA1328 KLF15 KLHL26 KPRP KRT31 KRT34 KRT39 KRT75 KRT83 KRTAP10-11 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP19-7 KRTAP4-2 KRTAP6-2 KRTAP9-3 LASP1 LHX2 LNX1 MBD3L1 MED20 MEOX2 MID2 MTUS2 NADSYN1 NBPF19 NEDD9 NHLRC2 NOTCH2NLA NUTM2F PIK3R3 PRDM6 PRKAR1B RANBP3 RB1 RIN1 RNF144B RORB RUSC1 SCN5A SH3KBP1 SHISA6 SLC15A2 SMARCD1 SORBS3 SPATA12 SPRED1 TOX2 TP53BP1 TRIM29 TRIT1 UBC USP54 USP7 YWHAG ZBTB32 ZBTB42 ZC2HC1C ZNF135
Entrez ID		22859	23294
HPRD ID		14305	10610
Ensembl ID		ENSG00000072071	ENSG00000064999
Uniprot IDs		O94910	Q05CP0 Q92625
PDB IDs			2LMR 2MYQ 6F7O
Enriched GO Terms of Interacting Partners?
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