IKZF2 and SPAG16

Data Source:
BioGRID (affinity chromatography technology)

		IKZF2	SPAG16
Description		IKAROS family zinc finger 2	sperm associated antigen 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Region Axoneme Sperm Flagellum Axonemal Central Apparatus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Molecular_function DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Biological_process	Sperm Axoneme Assembly Axoneme Assembly Cilium Assembly Cerebrospinal Fluid Circulation Mucociliary Clearance
Pathways
Drugs
Diseases
GWAS		C-reactive protein levels ( 30388399) Eosinophil counts ( 29403010 19198610 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Estimated glomerular filtration rate ( 31451708) Glaucoma (primary open-angle) ( 29891935) Heel bone mineral density ( 30598549) Lung cancer ( 28604730) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Neutrophil percentage of granulocytes ( 27863252) Selective IgA deficiency ( 27723758) Squamous cell lung carcinoma ( 28604730) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus ( 27399966 26502338) Systemic sclerosis ( 29293537) Type 2 diabetes ( 32499647)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Attention deficit hyperactivity disorder ( 30478444) Body mass index ( 25673413) Contrast sensitivity ( 24152035) Fasting insulin (dietary factor interaction) ( 24204828) HIV-associated neurocognitive disorder (mild neurocognitive disorder) ( 28447399) Homeostasis model assessment of insulin resistance (dietary factor interaction) ( 24204828) Initial pursuit acceleration ( 29064472) Obesity-related traits ( 23251661) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) Schizophrenia ( 30285260) Waist circumference ( 28552196)
Interacting Genes		9 interacting genes: AQP1 CTBP1 CTBP2 HDAC4 IKZF1 IKZF4 IKZF5 LONRF1 TCEANC	5 interacting genes: AP3M1 MEIG1 MRPL1 SPAG6 VEZF1
Entrez ID		22807	79582
HPRD ID		05872	18089
Ensembl ID		ENSG00000030419	ENSG00000144451
Uniprot IDs		A0A024R3Z4 Q9UKS7	B4DYB5 Q4G1A2 Q8N0X2
PDB IDs
Enriched GO Terms of Interacting Partners?
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