IKZF2 and IKZF5

Data Source:
HPRD (in vitro)

		IKZF2	IKZF5
Description		IKAROS family zinc finger 2	IKAROS family zinc finger 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Protein-containing Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Molecular_function DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Protein Domain Specific Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Biological_process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		C-reactive protein levels ( 30388399) Eosinophil counts ( 29403010 19198610 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Estimated glomerular filtration rate ( 31451708) Glaucoma (primary open-angle) ( 29891935) Heel bone mineral density ( 30598549) Lung cancer ( 28604730) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Neutrophil percentage of granulocytes ( 27863252) Selective IgA deficiency ( 27723758) Squamous cell lung carcinoma ( 28604730) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus ( 27399966 26502338) Systemic sclerosis ( 29293537) Type 2 diabetes ( 32499647)
Interacting Genes		9 interacting genes: AQP1 CTBP1 CTBP2 HDAC4 IKZF1 IKZF4 IKZF5 LONRF1 TCEANC	9 interacting genes: CCDC85B IKZF1 IKZF2 IKZF3 IKZF4 LDOC1 NUDT22 PIAS1 UBE2I
Entrez ID		22807	64376
HPRD ID		05872	05873
Ensembl ID		ENSG00000030419	ENSG00000095574
Uniprot IDs		A0A024R3Z4 Q9UKS7	Q9H5V7
PDB IDs
Enriched GO Terms of Interacting Partners?
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