IKZF5 and IKZF4

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		IKZF5	IKZF4
Description		IKAROS family zinc finger 5	IKAROS family zinc finger 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Protein-containing Complex	Nucleus Nucleoplasm Nuclear Body Protein-containing Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Protein Domain Specific Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Protein Domain Specific Binding BHLH Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Alopecia areata ( 20596022 25608926) Anorexia nervosa ( 28494655) Asthma ( 21804548 31959851 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Autoimmune traits (pleiotropy) ( 30572963) Brain morphology (MOSTest) ( 32665545) Cognitive ability (MTAG) ( 29186694) Cognitive function ( 25644384) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Neutrophil percentage of granulocytes ( 27863252) Refractive error ( 32231278) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Type 1 diabetes ( 21829393 25751624 18198356) Vitiligo ( 27723757 22561518)
Interacting Genes		9 interacting genes: CCDC85B IKZF1 IKZF2 IKZF3 IKZF4 LDOC1 NUDT22 PIAS1 UBE2I	20 interacting genes: CDC7 CHD4 CSNK1D FHL2 FOXP3 HDAC2 IKZF1 IKZF2 IKZF3 IKZF5 MCRS1 MOB1A MOB3C NFKBIA NRG1 SIN3A SIN3B TCAF1 TCEA2 TXK
Entrez ID		64376	64375
HPRD ID		05873	05874
Ensembl ID		ENSG00000095574	ENSG00000123411
Uniprot IDs		Q9H5V7	Q9H2S9
PDB IDs			2MA7
Enriched GO Terms of Interacting Partners?
Tagcloud ?
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