NID2 and PITX1

Data Source:
BioGRID (two hybrid)

		NID2	PITX1
Description		nidogen 2	paired like homeodomain 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Extracellular Space Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome	Chromatin Nucleus Transcription Regulator Complex Cytoplasm
	Molecular Function	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Collagen Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Cell Adhesion Cell-matrix Adhesion Extracellular Matrix Organization Basement Membrane Organization	Skeletal System Development Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Branchiomeric Skeletal Muscle Development Pituitary Gland Development Embryonic Hindlimb Morphogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Myoblast Fate Commitment Cartilage Development
Pathways		Laminin interactions Laminin interactions
Drugs
Diseases			Congenital clubfoot; Congenital talipes equinovarus
GWAS		Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 29875488) Body mass index ( 28892062) Craniofacial microsomia ( 26853712) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol levels ( 32203549) Lung cancer (smoking interaction) ( 24658283) Pulmonary function ( 17903307) Triglyceride levels ( 32203549 29403010) Waist-to-hip ratio adjusted for body mass index ( 26785701)	Atrial fibrillation ( 29237688) Bulimia nervosa ( 23568457) Colorectal cancer ( 30529582 24836286 23263487) Colorectal cancer or advanced adenoma ( 30510241) Height ( 20881960 25429064 23563607 31562340 18391951) Immune response to anthrax vaccine ( 22658931) Testicular germ cell tumor ( 28604732 23666240)
Interacting Genes		24 interacting genes: ANKRD13D CCN3 COL13A1 COL1A1 COL4A1 ELN GNE HOXC8 HSPG2 KPRP KRTAP1-3 KRTAP10-3 KRTAP6-2 LAMC1 LCE1A MAML3 PITX1 PLSCR4 RBP3 SKIL TFG UNKL ZNF581 ZNF774	98 interacting genes: ABHD11 AKAP8L ALG13 ANKRD10 ARID5A ATN1 BPIFA1 C10orf55 C11orf1 C19orf54 C1orf94 C9orf57 CDX4 CEACAM6 CYSRT1 DCTN3 DVL3 DZIP3 EFEMP2 EGR1 FAM168A FAM168B FOXO1 GATA1 GOLGA2 HGS HOXA1 HSF4 HYI IGFL2 IPO13 KLHL26 KRT34 KRT83 KRTAP13-1 KRTAP13-2 KRTAP19-5 KRTAP19-7 KRTAP26-1 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP8-1 LASP1 LZTS2 MAGED1 METTL27 MGAT5B MSX2 MYH7B MYOZ3 NEUROD1 NHLRC4 NID2 NR5A1 PFDN5 PLA2G10 PLEKHB2 PLSCR1 PLSCR3 POU1F1 PRR20A PRR20B PRR20C PRR20D PRR20E PSMB11 PTK6 RBPMS RFX6 RHOXF2 RNF31 ROR2 SERGEF SERPINE1 SIK1B SLC15A2 SMARCA2 SPAG8 STH TBX19 TBX22 TEKT5 TFAP2D TLE5 TP53BP1 TRAF1 TRAPPC2 TRIM23 TSC1 UFSP1 UPF2 VGLL3 YPEL3 ZBTB32 ZNF34
Entrez ID		22795	5307
HPRD ID		05654	03688
Ensembl ID		ENSG00000087303	ENSG00000069011
Uniprot IDs		Q14112	P78337 X5D9A5
PDB IDs
Enriched GO Terms of Interacting Partners?
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