NID2 and ELN

Data Source:
HPRD (in vitro)

		NID2	ELN
Description		nidogen 2	elastin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Extracellular Space Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome	Extracellular Region Extracellular Matrix Collagen-containing Extracellular Matrix Elastic Fiber
	Molecular Function	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Collagen Binding	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Constituent Conferring Elasticity Extracellular Matrix Binding
	Biological Process	Cell Adhesion Cell-matrix Adhesion Extracellular Matrix Organization Basement Membrane Organization	Outflow Tract Morphogenesis Aortic Valve Morphogenesis Skeletal Muscle Tissue Development Respiratory Gaseous Exchange By Respiratory System Blood Circulation Animal Organ Morphogenesis Extracellular Matrix Organization Regulation Of Actin Filament Polymerization Stress Fiber Assembly Regulation Of Smooth Muscle Cell Proliferation
Pathways		Laminin interactions Laminin interactions	Degradation of the extracellular matrix Elastic fibre formation Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs			Rofecoxib
Diseases			Congenital supravalvar aortic stenosis Cutis laxa, including: Autosomal dominant cutis laxa (ADCL); Autosomal recessive cutis laxa I (ARCL1); Autosomal recessive cutis laxa II (ARCL2); X-linked recessive cutis laxa (XRCL); Wrinkly skin syndrome
GWAS		Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 29875488) Body mass index ( 28892062) Craniofacial microsomia ( 26853712) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol levels ( 32203549) Lung cancer (smoking interaction) ( 24658283) Pulmonary function ( 17903307) Triglyceride levels ( 32203549 29403010) Waist-to-hip ratio adjusted for body mass index ( 26785701)	Diverticular disease ( 30177863) Height ( 31562340)
Interacting Genes		24 interacting genes: ANKRD13D CCN3 COL13A1 COL1A1 COL4A1 ELN GNE HOXC8 HSPG2 KPRP KRTAP1-3 KRTAP10-3 KRTAP6-2 LAMC1 LCE1A MAML3 PITX1 PLSCR4 RBP3 SKIL TFG UNKL ZNF581 ZNF774	22 interacting genes: ASS1 BGN CKMT2 CLU DCN ELANE FBLN1 FBLN2 FBN1 FBN2 FCN1 FKBP10 LGALS3 LOX LOXL1 LYZ MAGEH1 MFAP2 MTDH NID2 PRTN3 SPINK1
Entrez ID		22795	2006
HPRD ID		05654	00556
Ensembl ID		ENSG00000087303	ENSG00000049540
Uniprot IDs		Q14112	B3KRT8 B4E3S4 E7EN65 E7ENM0 G3V0G6 G5E950 P15502 Q59H17 Q6ZUN2 Q8NBI4
PDB IDs
Enriched GO Terms of Interacting Partners?
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