FGF3 and EBNA1BP2

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		FGF3	EBNA1BP2
Description		fibroblast growth factor 3	EBNA1 binding protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm	Chromosome Nucleolus Preribosome, Large Subunit Precursor Nuclear Periphery
	Molecular Function	Fibroblast Growth Factor Receptor Binding Protein Binding Growth Factor Activity	RNA Binding Protein Binding
	Biological Process	MAPK Cascade Positive Regulation Of Protein Phosphorylation Signal Transduction Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Anatomical Structure Morphogenesis Animal Organ Morphogenesis Positive Regulation Of Gene Expression Cell Differentiation Regulation Of Cell Migration Positive Regulation Of Cell Division Positive Regulation Of Protein Kinase B Signaling Negative Regulation Of Cardiac Muscle Tissue Development	RRNA Processing Ribosomal Large Subunit Biogenesis
Pathways		PI3K Cascade PIP3 activates AKT signaling FGFR1b ligand binding and activation FGFR2b ligand binding and activation Activated point mutants of FGFR2 Constitutive Signaling by Aberrant PI3K in Cancer Phospholipase C-mediated cascade: FGFR1 Phospholipase C-mediated cascade; FGFR2 Downstream signaling of activated FGFR1 SHC-mediated cascade:FGFR1 PI-3K cascade:FGFR1 FRS-mediated FGFR1 signaling PI-3K cascade:FGFR2 SHC-mediated cascade:FGFR2 FRS-mediated FGFR2 signaling Negative regulation of FGFR1 signaling Negative regulation of FGFR2 signaling Signaling by FGFR2 in disease FGFRL1 modulation of FGFR1 signaling RAF/MAP kinase cascade PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases		Kaposi's sarcoma
GWAS		Attention deficit hyperactivity disorder ( 29325848) Breast cancer ( 20453838) Childhood ear infection ( 27182965 28928442) Craniofacial microsomia ( 26853712) Lean body mass ( 28552196) Monobrow ( 27182965) Protein quantitative trait loci ( 18464913) Urate levels in overweight individuals ( 25811787) White blood cell count (basophil) ( 29403010)	Metabolite levels ( 23823483)
Interacting Genes		6 interacting genes: EBNA1BP2 FGFR1 FGFR2 FGFR3 FGFR4 RPS2	6 interacting genes: BRIX1 CEP70 FAM9B FBXW7 FGF3 GSK3A
Entrez ID		2248	10969
HPRD ID		01289	16849
Ensembl ID		ENSG00000186895	ENSG00000117395
Uniprot IDs		P11487	H7C2Q8 Q6IB29 Q99848
PDB IDs
Enriched GO Terms of Interacting Partners?
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