EBNA1BP2 and FGF3

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		EBNA1BP2	FGF3
Description		EBNA1 binding protein 2	fibroblast growth factor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome Nucleolus Preribosome, Large Subunit Precursor Nuclear Periphery	Extracellular Region Extracellular Space Cytoplasm
	Molecular Function	RNA Binding Protein Binding	Fibroblast Growth Factor Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	RRNA Processing Ribosomal Large Subunit Biogenesis	MAPK Cascade Positive Regulation Of Protein Phosphorylation Signal Transduction Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Anatomical Structure Morphogenesis Animal Organ Morphogenesis Positive Regulation Of Gene Expression Cell Differentiation Regulation Of Cell Migration Positive Regulation Of Cell Division Positive Regulation Of Protein Kinase B Signaling Negative Regulation Of Cardiac Muscle Tissue Development
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol	PI3K Cascade PIP3 activates AKT signaling FGFR1b ligand binding and activation FGFR2b ligand binding and activation Activated point mutants of FGFR2 Constitutive Signaling by Aberrant PI3K in Cancer Phospholipase C-mediated cascade: FGFR1 Phospholipase C-mediated cascade; FGFR2 Downstream signaling of activated FGFR1 SHC-mediated cascade:FGFR1 PI-3K cascade:FGFR1 FRS-mediated FGFR1 signaling PI-3K cascade:FGFR2 SHC-mediated cascade:FGFR2 FRS-mediated FGFR2 signaling Negative regulation of FGFR1 signaling Negative regulation of FGFR2 signaling Signaling by FGFR2 in disease FGFRL1 modulation of FGFR1 signaling RAF/MAP kinase cascade PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Drugs
Diseases			Kaposi's sarcoma
GWAS		Metabolite levels ( 23823483)	Attention deficit hyperactivity disorder ( 29325848) Breast cancer ( 20453838) Childhood ear infection ( 27182965 28928442) Craniofacial microsomia ( 26853712) Lean body mass ( 28552196) Monobrow ( 27182965) Protein quantitative trait loci ( 18464913) Urate levels in overweight individuals ( 25811787) White blood cell count (basophil) ( 29403010)
Interacting Genes		6 interacting genes: BRIX1 CEP70 FAM9B FBXW7 FGF3 GSK3A	6 interacting genes: EBNA1BP2 FGFR1 FGFR2 FGFR3 FGFR4 RPS2
Entrez ID		10969	2248
HPRD ID		16849	01289
Ensembl ID		ENSG00000117395	ENSG00000186895
Uniprot IDs		H7C2Q8 Q6IB29 Q99848	P11487
PDB IDs
Enriched GO Terms of Interacting Partners?
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