RNF152 and SERPINB7

Data Source:
HPRD (in vitro, two hybrid)

		RNF152	SERPINB7
Description		ring finger protein 152	serpin family B member 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Integral Component Of Organelle Membrane	Extracellular Space Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Small GTPase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Serine-type Endopeptidase Inhibitor Activity
	Biological Process	Apoptotic Process Positive Regulation Of Autophagy Protein Ubiquitination Cellular Response To Amino Acid Starvation Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Negative Regulation Of TORC1 Signaling	Negative Regulation Of Endopeptidase Activity Positive Regulation Of Transforming Growth Factor Beta1 Production Positive Regulation Of Collagen Biosynthetic Process Positive Regulation Of Glomerular Mesangial Cell Proliferation Positive Regulation Of Platelet-derived Growth Factor Production
Pathways		E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462 30604766) Glomerular filtration rate (creatinine) ( 28452372 26831199)	Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Asthma ( 31361310 30929738 32296059 31619474) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738) Asthma onset (childhood vs adult) ( 30929738) Food allergy ( 29051540) Hen's egg allergy ( 29051540) Systolic blood pressure ( 29208002)
Interacting Genes		10 interacting genes: CROCC EBP GJA8 KIR2DL3 RHEB RRAGA TSPAN12 UBE2E1 UBE2N UBE2W
Entrez ID		220441	8710
HPRD ID		11514	04524
Ensembl ID		ENSG00000176641	ENSG00000166396
Uniprot IDs		Q8N8N0	A8K3Q8 O75635
PDB IDs
Enriched GO Terms of Interacting Partners?
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