F13B and F13A1

Data Source:
HPRD (in vitro)

		F13B	F13A1
Description		coagulation factor XIII B chain	coagulation factor XIII A chain
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Extracellular Region Platelet Alpha Granule Lumen Collagen-containing Extracellular Matrix Blood Microparticle
	Molecular Function		Protein-glutamine Gamma-glutamyltransferase Activity Protein Binding Metal Ion Binding
	Biological Process	Blood Coagulation Negative Regulation Of Cellular Protein Catabolic Process	Platelet Degranulation Blood Coagulation Peptide Cross-linking Protein Phosphopantetheinylation Cytokine-mediated Signaling Pathway Blood Coagulation, Fibrin Clot Formation
Pathways		Common Pathway of Fibrin Clot Formation	Platelet degranulation Common Pathway of Fibrin Clot Formation Interleukin-4 and Interleukin-13 signaling
Drugs		Zinc Catridecacog Thrombin Human thrombin Zinc acetate	N-Acetyl-Serine Thrombin Prothrombin Human thrombin Anti-inhibitor coagulant complex
Diseases		Factor XIII deficiency	Factor XIII deficiency
GWAS		Age-related macular degeneration ( 23536807) Blood protein levels ( 28240269) Erectile dysfunction in type 1 diabetes ( 22704111) Lupus nephritis in systemic lupus erythematosus ( 24925725)	Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) End-stage coagulation ( 23381943) Entorhinal cortical volume ( 21116278) GIP levels in response to oral glucose tolerance test (120 minutes) ( 29093273) Interleukin-10 levels ( 22205395) Night sleep phenotypes ( 27126917) Response to lamotrigine and valproic acid in genetic generalized epilepsy ( 32308125) Type 2 diabetes (age of onset) ( 28060188) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		2 interacting genes: F13A1 FGG	13 interacting genes: ANXA7 CDKN1A F13B F2 FGA FGG FN1 NUDT21 PTK2 SERPINF2 SH3GL2 TK1 UFD1
Entrez ID		2165	2162
HPRD ID		00605	00604
Ensembl ID		ENSG00000143278	ENSG00000124491
Uniprot IDs		P05160	P00488
PDB IDs			1EVU 1EX0 1F13 1FIE 1GGT 1GGU 1GGY 1QRK 4KTY 5MHL 5MHM 5MHN 5MHO
Enriched GO Terms of Interacting Partners?
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