F13A1 and F13B

Data Source:
HPRD (in vitro)

		F13A1	F13B
Description		coagulation factor XIII A chain	coagulation factor XIII B chain
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Platelet Alpha Granule Lumen Collagen-containing Extracellular Matrix Blood Microparticle	Extracellular Region
	Molecular Function	Protein-glutamine Gamma-glutamyltransferase Activity Protein Binding Metal Ion Binding
	Biological Process	Platelet Degranulation Blood Coagulation Peptide Cross-linking Protein Phosphopantetheinylation Cytokine-mediated Signaling Pathway Blood Coagulation, Fibrin Clot Formation	Blood Coagulation Negative Regulation Of Cellular Protein Catabolic Process
Pathways		Platelet degranulation Common Pathway of Fibrin Clot Formation Interleukin-4 and Interleukin-13 signaling	Common Pathway of Fibrin Clot Formation
Drugs		N-Acetyl-Serine Thrombin Prothrombin Human thrombin Anti-inhibitor coagulant complex	Zinc Catridecacog Thrombin Human thrombin Zinc acetate
Diseases		Factor XIII deficiency	Factor XIII deficiency
GWAS		Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) End-stage coagulation ( 23381943) Entorhinal cortical volume ( 21116278) GIP levels in response to oral glucose tolerance test (120 minutes) ( 29093273) Interleukin-10 levels ( 22205395) Night sleep phenotypes ( 27126917) Response to lamotrigine and valproic acid in genetic generalized epilepsy ( 32308125) Type 2 diabetes (age of onset) ( 28060188) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Age-related macular degeneration ( 23536807) Blood protein levels ( 28240269) Erectile dysfunction in type 1 diabetes ( 22704111) Lupus nephritis in systemic lupus erythematosus ( 24925725)
Interacting Genes		13 interacting genes: ANXA7 CDKN1A F13B F2 FGA FGG FN1 NUDT21 PTK2 SERPINF2 SH3GL2 TK1 UFD1	2 interacting genes: F13A1 FGG
Entrez ID		2162	2165
HPRD ID		00604	00605
Ensembl ID		ENSG00000124491	ENSG00000143278
Uniprot IDs		P00488	P05160
PDB IDs		1EVU 1EX0 1F13 1FIE 1GGT 1GGU 1GGY 1QRK 4KTY 5MHL 5MHM 5MHN 5MHO
Enriched GO Terms of Interacting Partners?
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