F2RL2 and AMT

Data Source:
BioGRID (two hybrid)

		F2RL2	AMT
Description		coagulation factor II thrombin receptor like 2	aminomethyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane Protein-containing Complex	Nucleoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	Phosphatidylinositol Phospholipase C Activity G Protein-coupled Receptor Activity Protein Binding Thrombin-activated Receptor Activity	Aminomethyltransferase Activity Transaminase Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway Blood Coagulation Response To Wounding Platelet Activation Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Thrombin-activated Receptor Signaling Pathway	Glycine Catabolic Process Glycine Decarboxylation Via Glycine Cleavage System
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs)	Glycine degradation
Drugs			Tetrahydrofolic acid NADH 5-methyltetrahydrofolic acid
Diseases			Nonketotic hyperglycinemia; Glycine encephalopathy (GCE)
GWAS		Mean platelet volume ( 28031487) Phenylephrine infusion rate during anesthesia ( 31455332)	Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Coronary artery disease ( 29212778) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Depressive symptom (depressed mood) (binary trait) ( 31530331) Depressive symptoms (binary sum-score) ( 31530331) Extremely high intelligence ( 29520040) Gut microbiota (functional units) ( 27694959) Inflammatory bowel disease ( 28067908) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		8 interacting genes: CDH5 CTSG ECT2 F11R F2 F2RL3 JAM2 JAM3	2 interacting genes: PDLIM4 VAC14
Entrez ID		2151	275
HPRD ID		03561	01997
Ensembl ID		ENSG00000164220	ENSG00000145020
Uniprot IDs		O00254	A0A024R2U7 P48728
PDB IDs			1WSR 1WSV
Enriched GO Terms of Interacting Partners?
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