ETV2 and KDM3A

Data Source:
BioGRID (pull down)

		ETV2	KDM3A
Description		ETS variant transcription factor 2	lysine demethylase 3A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Histone Deacetylase Complex Chromatin Nucleus Nucleoplasm Cytoplasm Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding	Transcription Coregulator Activity Iron Ion Binding Protein Binding Chromatin DNA Binding Histone Demethylase Activity (H3-K9 Specific) Androgen Receptor Binding Dioxygenase Activity
	Biological Process	Blastocyst Development Placenta Development Regulation Of Transcription By RNA Polymerase II Notch Signaling Pathway Wnt Signaling Pathway Cell Differentiation Erythrocyte Differentiation Positive Regulation Of Endothelial Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Blood Vessel Morphogenesis BMP Signaling Pathway Involved In Mesodermal Cell Fate Specification Positive Regulation Of Mesoderm Development	Regulation Of Transcription By RNA Polymerase II Spermatid Nucleus Elongation Hormone-mediated Signaling Pathway Androgen Receptor Signaling Pathway Histone H3-K9 Demethylation Histone H3-K9 Dimethylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Formaldehyde Biosynthetic Process Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Cold-induced Thermogenesis Cellular Response To Leukemia Inhibitory Factor Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Differentiation
Pathways			HDMs demethylate histones NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)	Atrial fibrillation ( 29892015) Glomerular filtration rate in chronic kidney disease ( 26420894) Ovarian cancer ( 30557369)
Interacting Genes		1 interacting genes: KDM3A	6 interacting genes: ETV2 H3C14 MRTFA MRTFB MYOCD RIPK2
Entrez ID		2116	55818
HPRD ID		16871	11054
Ensembl ID		ENSG00000105672	ENSG00000115548
Uniprot IDs		K7ERX2 O00321 Q3KNT2	Q9Y4C1
PDB IDs
Enriched GO Terms of Interacting Partners?
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