TSNARE1 and MFSD14B

Data Source:
BioGRID (two hybrid)

		TSNARE1	MFSD14B
Description		t-SNARE domain containing 1	major facilitator superfamily domain containing 14B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endomembrane System Integral Component Of Membrane SNARE Complex	Integral Component Of Membrane
	Molecular Function	SNARE Binding SNAP Receptor Activity	Protein Binding Transmembrane Transporter Activity
	Biological Process	Intracellular Protein Transport Vesicle Fusion Vesicle Docking	Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Anxiety/tension (special factor of neuroticism) ( 30867560) Autism spectrum disorder or schizophrenia ( 28540026) Body size at age 10 ( 32376654) Broad depression or schizophrenia ( 30626913) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive decline rate in late mild cognitive impairment ( 26252872) Feeling nervous ( 29500382) Feeling tense ( 29500382) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Intelligence (MTAG) ( 29326435) Mental health study participation (completed survey) ( 31263887) Monoclonal gammopathy of undetermined significance ( 30737484) Schizophrenia ( 28991256 25056061 29483656 30285260 23974872) Systolic blood pressure ( 30224653 30578418)
Interacting Genes		27 interacting genes: CD79A CNIH4 CYB561 DYNLL1 EBP ELOVL4 ELOVL5 GPR152 JAGN1 LEPROTL1 LMNA MFSD14B REEP4 RETREG3 SEC11C SLC10A6 SLC35C2 SNAP29 STX1A TM4SF19 TMEM229B TMEM51 TMEM86B TMX2 VEZT YIPF4 ZDHHC15	75 interacting genes: ADIPOQ AGPAT3 AGPAT4 ARL6IP1 ATP13A1 BNIP3 C14orf180 C4orf3 CCL4L2 CFHR5 CLDN4 CMTM3 COMT CSGALNACT2 CTSA CYB5B CYBC1 DEFB127 DNAJC30 EMC6 ERG28 FKBP8 FMO1 FUNDC2 GIMAP1 GOSR2 GRM2 KTN1 LAT LEPROTL1 LPCAT2 LRP10 MGLL MS4A1 NAT8 ORMDL1 PEX16 PKMYT1 PRRT2 RNF24 SACM1L SCD SERP1 SERP2 SLC25A46 SLC39A9 SLC66A2 SMAGP STX3 TECR THSD7B TIMMDC1 TMBIM6 TMEM119 TMEM167B TMEM176A TMEM19 TMEM208 TMEM229B TMEM239 TMEM31 TMX2 TPRG1 TRARG1 TREX1 TSNARE1 UBE2J1 UNC50 USE1 YIPF1 YIPF2 YIPF4 YIPF6 ZDHHC24 ZFPL1
Entrez ID		203062	84641
HPRD ID		08708	07869
Ensembl ID		ENSG00000171045	ENSG00000148110
Uniprot IDs		E5RHT3 Q6P186 Q96NA8	Q5SR56
PDB IDs
Enriched GO Terms of Interacting Partners?
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