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TEX37 and ANAPC11
Data Source:
BioGRID
(two hybrid)
TEX37
ANAPC11
Description
testis expressed 37
anaphase promoting complex subunit 11
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Nucleus
Nucleoplasm
Anaphase-promoting Complex
Nucleolus
Cytosol
Cullin-RING Ubiquitin Ligase Complex
Molecular Function
Protein Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ubiquitin-ubiquitin Ligase Activity
Ubiquitin Protein Ligase Activity
Cullin Family Protein Binding
Biological Process
Mitotic Cell Cycle
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Anaphase-promoting Complex-dependent Catabolic Process
Positive Regulation Of Mitotic Metaphase/anaphase Transition
Cell Division
Protein K11-linked Ubiquitination
Regulation Of Mitotic Cell Cycle Phase Transition
Pathways
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
CDK-mediated phosphorylation and removal of Cdc6
Transcriptional Regulation by VENTX
Aberrant regulation of mitotic exit in cancer due to RB1 defects
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Interacting Genes
44 interacting genes:
ANAPC11
APP
ATXN1L
BSCL2
CAMK2A
CTRC
CYSRT1
DAZAP2
FOXD2
HOXC9
KCTD9
KLHDC7B
KPNA3
KRTAP12-2
KRTAP12-4
KRTAP13-2
KRTAP19-5
KRTAP19-7
KRTAP23-1
KRTAP26-1
KRTAP3-1
KRTAP6-2
MAGEA11
OTX1
PITX2
PLAC8
PRR30
RBFOX1
RBFOX2
RBPMS
RBPMS2
RNF44
SOX14
TFAP2D
TFG
TLE5
TLX3
TRIP13
UBAP2
VAC14
VGLL3
WWOX
ZBTB32
ZC3H10
55 interacting genes:
ANAPC10
ANAPC2
ANAPC4
BANP
BEND2
CAPN11
CCNB1
CDC16
CDC20
CREB5
CRYBA2
CUL5
CYSRT1
DTX2
EFEMP1
EFEMP2
FBXO5
FRS3
FZR1
GPANK1
HSD3B7
IQUB
KRTAP11-1
KRTAP13-2
KRTAP19-2
KRTAP3-1
KRTAP3-3
KRTAP6-1
KRTAP6-2
MAK
MGAT5B
MLKL
NKD2
OXER1
P4HA3
PRKAA2
PRKAB2
PTTG1
RBPMS
RNF111
TCEANC
TEX37
TLE5
TRIM65
UBC
UBE2C
UBE2D1
UBE2D2
UBE2D3
UBE2K
UBE2L1
UBE2S
UBE2U
WWOX
ZAP70
Entrez ID
200523
51529
HPRD ID
08688
12452
Ensembl ID
ENSG00000172073
ENSG00000141552
Uniprot IDs
A0A140VK60
Q96LM6
A0A024R8S1
Q9NYG5
PDB IDs
2MT5
4R2Y
4UI9
5A31
5G04
5G05
5JG6
5KHR
5KHU
5L9T
5L9U
5LCW
6Q6G
6Q6H
6TLJ
6TM5
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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