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AHSG and DCN
Data Source:
BioGRID
(pull down)
HPRD
(in vitro)
AHSG
DCN
Description
alpha 2-HS glycoprotein
decorin
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Endoplasmic Reticulum Lumen
Golgi Apparatus
Extracellular Matrix
Platelet Alpha Granule Lumen
Secretory Granule Lumen
Collagen-containing Extracellular Matrix
Extracellular Exosome
Blood Microparticle
Extracellular Region
Collagen Type VI Trimer
Extracellular Space
Golgi Lumen
Lysosomal Lumen
Collagen-containing Extracellular Matrix
Molecular Function
Endopeptidase Inhibitor Activity
Cysteine-type Endopeptidase Inhibitor Activity
Kinase Inhibitor Activity
RNA Binding
Protein Binding
Collagen Binding
Glycosaminoglycan Binding
Extracellular Matrix Structural Constituent Conferring Compression Resistance
Protein N-terminus Binding
Extracellular Matrix Binding
Biological Process
Skeletal System Development
Platelet Degranulation
Pinocytosis
Acute-phase Response
Negative Regulation Of Endopeptidase Activity
Regulation Of Bone Mineralization
Negative Regulation Of Bone Mineralization
Negative Regulation Of Kinase Activity
Neutrophil Degranulation
Post-translational Protein Modification
Cellular Protein Metabolic Process
Negative Regulation Of Insulin Receptor Signaling Pathway
Regulation Of Inflammatory Response
Positive Regulation Of Phagocytosis
Kidney Development
Placenta Development
Skeletal Muscle Tissue Development
Aging
Response To Mechanical Stimulus
Animal Organ Morphogenesis
Positive Regulation Of Autophagy
Negative Regulation Of Endothelial Cell Migration
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Positive Regulation Of Macroautophagy
Negative Regulation Of Angiogenesis
Peptide Cross-linking Via Chondroitin 4-sulfate Glycosaminoglycan
Extracellular Matrix Organization
Chondroitin Sulfate Biosynthetic Process
Chondroitin Sulfate Catabolic Process
Dermatan Sulfate Biosynthetic Process
Response To Lipopolysaccharide
Wound Healing
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Mitochondrial Depolarization
Positive Regulation Of Mitochondrial Fission
Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway
Pathways
Platelet degranulation
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Neutrophil degranulation
Post-translational protein phosphorylation
Degradation of the extracellular matrix
A tetrasaccharide linker sequence is required for GAG synthesis
Chondroitin sulfate biosynthesis
Dermatan sulfate biosynthesis
CS/DS degradation
ECM proteoglycans
ECM proteoglycans
Defective B4GALT7 causes EDS, progeroid type
Defective B3GAT3 causes JDSSDHD
Defective CHST3 causes SEDCJD
Defective CHST14 causes EDS, musculocontractural type
Defective CHSY1 causes TPBS
Defective B3GALT6 causes EDSP2 and SEMDJL1
Drugs
Zinc
Copper
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Diseases
Congenital stromal corneal dystrophy (CSCD); Congenital hereditary stromal dystrophy; Witschel dystrophy
GWAS
Activated partial thromboplastin time (
22703881
)
Blood protein levels (
30072576
29875488
28240269
)
Blood protein levels (
30072576
)
Central corneal thickness (
32528159
29760442
)
Heel bone mineral density (
30598549
)
Intraocular pressure (
29617998
)
Refractive error (
32231278
)
Sudden cardiac arrest (
21658281
)
Interacting Genes
8 interacting genes:
CDC42
DCN
FBXO2
FBXW7
GRB2
INSR
RRAS2
VKORC1
30 interacting genes:
AHSG
BRCA1
C1QA
CCN4
COL14A1
COL1A1
COL1A2
COL4A1
COL4A3
COL4A4
COL4A5
COL4A6
COL5A1
COL6A1
DPT
EGFR
ELN
FBN1
FLNA
FN1
MET
MMP2
MMP3
MMP7
PLA2G2A
SFTPD
TGFB1
TGFB2
THBS1
TNF
Entrez ID
197
1634
HPRD ID
00727
00501
Ensembl ID
ENSG00000145192
ENSG00000011465
Uniprot IDs
P02765
A0A024RBG6
P07585
Q6FH10
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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