PLPP4 and PSCA

Data Source:
BioGRID (two hybrid)

		PLPP4	PSCA
Description		phospholipid phosphatase 4	prostate stem cell antigen
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Extracellular Region Plasma Membrane Anchored Component Of Membrane Extracellular Exosome
	Molecular Function	Diacylglycerol Diphosphate Phosphatase Activity Protein Binding Phosphatidate Phosphatase Activity Identical Protein Binding	Acetylcholine Receptor Binding
	Biological Process	Blastocyst Hatching Phospholipid Metabolic Process Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Phospholipid Dephosphorylation Regulation Of Calcium Ion Import	Negative Regulation Of ERK1 And ERK2 Cascade Regulation Of Neurotransmitter Receptor Activity
Pathways		Role of phospholipids in phagocytosis	Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS			Bladder cancer ( 32117775 24163127 20972438 19648920) Blood urea nitrogen levels ( 31152163) Duodenal ulcer ( 22387998) Gastric adenocarcinoma (histologically verified) ( 26098866) Gastric atrophy ( 30753327) Gastric cancer ( 30189721 26098866) Non-cardia gastric cancer ( 26701879) Optic disc size ( 31809533) Pepsinogen I/II ratio ( 30753327) Severe gastric atrophy ( 30753327) Urinary tract infection frequency ( 28928442) Vertical cup-disc ratio ( 28073927)
Interacting Genes		33 interacting genes: ANKRD46 ARL13B BCL2L13 BIK BMP10 CD74 CISD2 CPLX4 CREB3L1 CYB5B ERGIC3 EVI2A FAM209A FRMD3 GET1 GJA1 GJB5 GPX8 LMNA LRRC59 MGST3 PAGE1 PDZK1IP1 PSCA SGPL1 SLC35A1 SSMEM1 STX1A STX2 SYT2 TMEM139 TMEM45B UPK1B	43 interacting genes: AGPAT5 AIG1 APOA2 APOL2 BCL2L2 BRICD5 CD53 CDIPT CMTM5 CTSA CYB561D2 DERL3 ERG28 INSIG2 JAGN1 LAT MOSPD3 PLP2 PLPP4 RUSF1 SLC16A4 SLC30A8 SLC35A1 SLC7A1 SMIM3 ST6GAL2 STX8 SYS1 TMEM140 TMEM147 TMEM218 TMEM239 TMEM243 TMEM262 TMEM42 TMEM54 TMEM86B TMEM97 TRARG1 TSPO2 UNC93A VAMP4 YIPF6
Entrez ID		196051	8000
HPRD ID		18745	03919
Ensembl ID		ENSG00000203805	ENSG00000167653
Uniprot IDs		B7Z3R3 Q5VZY2	D3DWI6 O43653
PDB IDs
Enriched GO Terms of Interacting Partners?
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