AGXT and KRTAP3-1

Data Source:
BioGRID (two hybrid)

		AGXT	KRTAP3-1
Description		alanine--glyoxylate and serine--pyruvate aminotransferase	keratin associated protein 3-1
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Matrix Peroxisome Peroxisomal Matrix Cytosol Intracellular Membrane-bounded Organelle	Cytosol Keratin Filament
	Molecular Function	Serine-pyruvate Transaminase Activity Protein Binding Alanine-glyoxylate Transaminase Activity Transaminase Activity Amino Acid Binding Pyridoxal Phosphate Binding Identical Protein Binding Protein Homodimerization Activity Protein Self-association	Structural Molecule Activity Protein Binding
	Biological Process	Protein Targeting To Peroxisome Glyoxylate Catabolic Process Glycine Biosynthetic Process, By Transamination Of Glyoxylate L-cysteine Catabolic Process Cellular Nitrogen Compound Metabolic Process L-alanine Catabolic Process Pyruvate Biosynthetic Process Glyoxylate Metabolic Process Response To Glucocorticoid Response To CAMP	Keratinization
Pathways		Glyoxylate metabolism and glycine degradation Peroxisomal protein import Peroxisomal protein import	Keratinization
Drugs		Pyridoxal phosphate Serine Glycine Alanine Aminooxyacetic acid N(6)-(pyridoxal phosphate)-L-lysine 4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID
Diseases		Primary hyperoxaluria (HP)
GWAS		Blood metabolite levels ( 24816252) Height ( 25282103 31562340) Urinary metabolites ( 26352407)
Interacting Genes		39 interacting genes: ACAT1 ATXN1L BATF3 C11orf1 C19orf54 CHIC2 CYSRT1 EFS FAM168B FHL5 FNTB FOSB GLP1R HOXA1 KRT31 KRT34 KRT37 KRT40 KRTAP1-1 KRTAP12-3 KRTAP3-1 KRTAP6-3 KRTAP8-1 KRTAP9-2 LPXN MDFI MORN5 NBPF19 NOTCH2NLA OIP5 PEX5 PLA2G10 PRDM6 PRICKLE4 RFX6 SNCAIP SPRYD7 TRAPPC14 TTC19	82 interacting genes: ADAM12 AGXT ANAPC11 BMP7 C20orf85 CDKN1A CELA2B CERK CFP CNNM3 CREB5 CTRC CYSRT1 DMRT3 DOCK2 FAM168A FAM222B FOXH1 FRS3 GATA2 GNE GPS2 GSTP1 HCK HEY2 HOXB9 HR HSF4 IL16 ITGB4 KRTAP10-8 KRTAP13-2 KRTAP13-3 KRTAP15-1 KRTAP26-1 KRTAP4-11 KRTAP4-12 KRTAP6-1 KRTAP9-3 KRTAP9-8 LCE1B LCE2B LCE3A LCE3D LCE4A LCE5A LMO4 LRRC41 MAPKBP1 MRPL40 MYPOP NOTCH2NLA NTAQ1 OTX1 PATZ1 PCSK5 PHLDA1 PKIB PLSCR4 POLR1C PPP1R32 PTPMT1 PVR RBPMS RECK REEP6 RNF44 SAMD7 SMARCC1 SPAG8 TEKT3 TEX37 TLX3 TNS2 VASN VENTX VGLL3 WDR25 YPEL3 ZFHX2 ZNF414 ZNF446
Entrez ID		189	83896
HPRD ID		05048	13937
Ensembl ID		ENSG00000172482	ENSG00000212901
Uniprot IDs		P21549	Q9BYR8
PDB IDs		1H0C 1J04 2YOB 3R9A 4CBR 4CBS 4I8A 4KXK 4KYO 5F9S 5HHY 5LUC 5OFY 5OG0 6RV0 6RV1
Enriched GO Terms of Interacting Partners?
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