E4F1 and ANP32A

Data Source:
HPRD (two hybrid, in vivo)

		E4F1	ANP32A
Description		E4F transcription factor 1	acidic nuclear phosphoprotein 32 family member A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Spindle	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Transferase Activity CAMP Response Element Binding Metal Ion Binding	RNA Binding Protein Binding Histone Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Replication Regulation Of Transcription By RNA Polymerase II Regulation Of Mitotic Cell Cycle, Embryonic Regulation Of Cell Cycle Process Viral Process Protein Ubiquitination Regulation Of Growth Positive Regulation Of Transcription By RNA Polymerase II Cell Division Mitotic Cell Cycle Arrest	Nucleocytoplasmic Transport Intracellular Signal Transduction Regulation Of Apoptotic Process Regulation Of MRNA Stability
Pathways			HuR (ELAVL1) binds and stabilizes mRNA
Drugs
Diseases
GWAS			Esophageal cancer ( 21642993)
Interacting Genes		14 interacting genes: ANP32A ATM ATR CDKN2A EHMT2 HMGA2 KRTAP10-4 KRTAP10-7 PRKDC RASSF1 RB1 SMAD9 TP53 UPF2	29 interacting genes: ADAP1 APEX1 ATXN1 AXIN1 CHAF1A E4F1 ELAVL1 H2AC20 H2BC21 H3-4 H3C1 H3C15 H4-16 H4C1 HSPB3 KPNA1 KPNA5 KPNA6 LHX3 MAP1B NSFL1C PCBP1 PGR PPARG PTPRC SET TAF1A THRB XPO1
Entrez ID		1877	8125
HPRD ID		04317	09014
Ensembl ID		ENSG00000167967	ENSG00000140350
Uniprot IDs		Q66K89	A0A384P5U2 P39687
PDB IDs			2JE0 2JE1 4XOS
Enriched GO Terms of Interacting Partners?
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