DPYSL3 and DPYSL5

Data Source:
HPRD (in vivo)

		DPYSL3	DPYSL5
Description		dihydropyrimidinase like 3	dihydropyrimidinase like 5
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GO Annotations	Cellular Component	Extracellular Space Cytosol Lamellipodium Growth Cone Filamentous Actin Cell Body Synapse Exocytic Vesicle	Cytosol Dendrite Neuronal Cell Body
	Molecular Function	Dihydropyrimidinase Activity Protein Binding SH3 Domain Binding Filamin Binding Chondroitin Sulfate Binding Identical Protein Binding	Dihydropyrimidinase Activity Protein Binding Microtubule Binding
	Biological Process	Pyrimidine Nucleobase Catabolic Process Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Negative Regulation Of Cell Migration Neuron Development Response To Axon Injury Actin Filament Bundle Assembly Positive Regulation Of Filopodium Assembly Actin Crosslink Formation Cellular Response To Cytokine Stimulus	Pyrimidine Nucleobase Catabolic Process Signal Transduction Nervous System Development Axon Guidance
Pathways		CRMPs in Sema3A signaling	CRMPs in Sema3A signaling
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Excessive daytime sleepiness ( 27992416) Metabolite levels ( 23823483) Subcortical volume (MOSTest) ( 32665545)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Fasting blood glucose ( 22581228) Fasting blood glucose (BMI interaction) ( 22581228) Obesity-related traits ( 23251661) Reflection (response to stress) ( 30886212) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urate levels ( 31578528) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) White blood cell count ( 32888494)
Interacting Genes		9 interacting genes: ACD CRMP1 DISC1 DPYSL2 DPYSL5 OTUD6A POT1 TERF1 TNIK	9 interacting genes: APPL1 CFAP161 DARS2 DPYS DPYSL2 DPYSL3 DPYSL4 FES HSPA5
Entrez ID		1809	56896
HPRD ID		03104	10522
Ensembl ID		ENSG00000113657	ENSG00000157851
Uniprot IDs		A0A140VK07 Q14195 Q6DEN2 Q8IXW6	Q9BPU6
PDB IDs		4BKN 4CNS 4CNT 4CNU	4B90 4B91 4B92
Enriched GO Terms of Interacting Partners?
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