DOK1 and PTPRH

Data Source:
HPRD (in vivo)

		DOK1	PTPRH
Description		docking protein 1	protein tyrosine phosphatase receptor type H
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Perinuclear Region Of Cytoplasm	Cytoplasm Integral Component Of Plasma Membrane Apical Plasma Membrane Microvillus Membrane
	Molecular Function	Protein Binding	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding Cadherin Binding
	Biological Process	Signal Transduction Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Ras Protein Signal Transduction Axon Guidance Macrophage Colony-stimulating Factor Signaling Pathway Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway	Protein Dephosphorylation Apoptotic Process Peptidyl-tyrosine Dephosphorylation
Pathways		PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 RET signaling
Drugs
Diseases
GWAS		Height ( 31562340)	Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systemic lupus erythematosus ( 28714469)
Interacting Genes		41 interacting genes: ABL1 ABL2 BCR CRK CRKL CSK DOK3 ERBB2 FES FGR FYN GRB10 HCK INPP5D INSR ITGB1 ITGB2 ITGB3 ITGB5 ITGB7 ITK KIT LCK LYN MAP4K4 NCK1 NCK2 PIK3R1 PLCG1 PTK6 PTPN6 PTPRH RASA1 RET SH2D1A SHC1 SRC TEC TLN1 VAV1 YES1	15 interacting genes: BCAR1 CRK DHPS DOK1 EGFR ERBB3 ERBB4 GHR KRTAP10-3 KRTAP10-8 LCK MAPK1 MLH1 PTK2 PXN
Entrez ID		1796	5794
HPRD ID		04228	03942
Ensembl ID		ENSG00000115325	ENSG00000080031
Uniprot IDs		B3KP83 B4DJN1 Q14CB2 Q2TA81 Q99704	Q9HD43
PDB IDs		2V76
Enriched GO Terms of Interacting Partners?
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