DYNC1I2 and ATP5MC3

Data Source:
BioGRID (affinity chromatography technology)

		DYNC1I2	ATP5MC3
Description		dynein cytoplasmic 1 intermediate chain 2	ATP synthase membrane subunit c locus 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Vesicle	Mitochondrial Proton-transporting ATP Synthase Complex, Coupling Factor F(o) Mitochondrial Outer Membrane Integral Component Of Membrane Proton-transporting ATP Synthase Complex, Coupling Factor F(o)
	Molecular Function	Microtubule Motor Activity Protein Binding Dynein Light Chain Binding Dynein Heavy Chain Binding	Lipid Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Microtubule-based Movement Regulation Of G2/M Transition Of Mitotic Cell Cycle Transport Along Microtubule Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Ciliary Basal Body-plasma Membrane Docking	ATP Biosynthetic Process ATP Synthesis Coupled Proton Transport Cristae Formation Mitochondrial ATP Synthesis Coupled Proton Transport
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Regulation of PLK1 Activity at G2/M Transition HSP90 chaperone cycle for steroid hormone receptors (SHR) Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase AURKA Activation by TPX2 HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation	Formation of ATP by chemiosmotic coupling Cristae formation
Drugs
Diseases
GWAS		Hippocampal volume ( 25625606) Metabolite levels ( 23823483) Refractive error ( 32231278) Weight ( 28552196)
Interacting Genes		8 interacting genes: CCDC136 DCTN1 DYNLRB1 DYNLT1 DYNLT3 NECAB2 PNN PPFIA1	5 interacting genes: ABHD16A GLP1R MTNR1A TMEM31 VKORC1
Entrez ID		1781	518
HPRD ID		04512	04112
Ensembl ID		ENSG00000077380	ENSG00000154518
Uniprot IDs		A0A140VKE9 B4DPZ3 Q13409	P48201
PDB IDs		5JPW 6F1T 6F1U 6F1Z 6F38 6F3A
Enriched GO Terms of Interacting Partners?
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