DIAPH1 and XPO6

Data Source:
HPRD (in vitro)

		DIAPH1	XPO6
Description		diaphanous related formin 1	exportin 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Organizing Center Cytosol Plasma Membrane Secretory Granule Membrane Ruffle Membrane Mitotic Spindle Ficolin-1-rich Granule Membrane	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Protein-containing Complex
	Molecular Function	RNA Binding Actin Binding Signaling Receptor Binding Protein Binding Ion Channel Binding	Nuclear Export Signal Receptor Activity Protein Binding
	Biological Process	Cytoskeleton Organization Sensory Perception Of Sound Regulation Of Cell Shape Actin Cytoskeleton Organization Actin Filament Polymerization Regulation Of Microtubule-based Process Protein Localization To Microtubule Neutrophil Degranulation Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Cytoskeleton Organization Cellular Response To Histamine Regulation Of Cell Motility	Protein Export From Nucleus
Pathways		RHO GTPases Activate Formins ERBB2 Regulates Cell Motility Neutrophil degranulation
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Mean platelet volume ( 32888494 27863252) Refractive error ( 32231278) Triglyceride levels ( 32203549)	Apolipoprotein A1 levels ( 32203549) Refractive error ( 32231278)
Interacting Genes		17 interacting genes: APBB1 BAIAP2 CDC42 CDC7 CENPA GAS7 NEDD4 PAX6 PKD2 PRPF40A PTPRF RAC1 RHOA RHOC TCERG1 WBP4 XPO6	6 interacting genes: ACTB DIAPH1 NUP62 PFN1 SMAD3 VASP
Entrez ID		1729	23214
HPRD ID		03670	10525
Ensembl ID		ENSG00000131504	ENSG00000169180
Uniprot IDs		A0A2R8Y5N1 O60610 Q6URC4	Q96QU8
PDB IDs
Enriched GO Terms of Interacting Partners?
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