DIAPH1 and WBP4

Data Source:
BioGRID (pull down)

		DIAPH1	WBP4
Description		diaphanous related formin 1	WW domain binding protein 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Organizing Center Cytosol Plasma Membrane Secretory Granule Membrane Ruffle Membrane Mitotic Spindle Ficolin-1-rich Granule Membrane	Nucleus Nucleoplasm Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome
	Molecular Function	RNA Binding Actin Binding Signaling Receptor Binding Protein Binding Ion Channel Binding	RNA Binding Protein Binding Zinc Ion Binding Proline-rich Region Binding
	Biological Process	Cytoskeleton Organization Sensory Perception Of Sound Regulation Of Cell Shape Actin Cytoskeleton Organization Actin Filament Polymerization Regulation Of Microtubule-based Process Protein Localization To Microtubule Neutrophil Degranulation Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Cytoskeleton Organization Cellular Response To Histamine Regulation Of Cell Motility	MRNA Splicing, Via Spliceosome RNA Splicing MRNA Cis Splicing, Via Spliceosome
Pathways		RHO GTPases Activate Formins ERBB2 Regulates Cell Motility Neutrophil degranulation	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Mean platelet volume ( 32888494 27863252) Refractive error ( 32231278) Triglyceride levels ( 32203549)	Crohn's disease ( 23266558) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Intraocular pressure ( 29617998) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269)
Interacting Genes		17 interacting genes: APBB1 BAIAP2 CDC42 CDC7 CENPA GAS7 NEDD4 PAX6 PKD2 PRPF40A PTPRF RAC1 RHOA RHOC TCERG1 WBP4 XPO6	54 interacting genes: ARGLU1 BUB3 CAPRIN1 CHERP CHTF8 CPSF6 CPSF7 DDX23 DDX3X DHX15 DHX38 DIAPH1 DNM2 EFTUD2 EWSR1 FAM50B FUS HLTF HNRNPK HNRNPU HTATSF1 ISY1 KHDRBS1 NONO PABPC1 PPIA PRPF3 PRPF4 PRPF40A PSPC1 SART1 SCAF4 SF1 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SNRNP200 SNRNP70 SNRPA SNRPB SNW1 TCERG1 TIA1 WAS WBP11 WDR83 WIPF1 XRCC6 ZC2HC1A ZNF207
Entrez ID		1729	11193
HPRD ID		03670	16086
Ensembl ID		ENSG00000131504	ENSG00000120688
Uniprot IDs		A0A2R8Y5N1 O60610 Q6URC4	O75554
PDB IDs			2DK1 2JXW 5O9Z 6AHD
Enriched GO Terms of Interacting Partners?
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