SSBP4 and IL36RN

Data Source:
HPRD (two hybrid)

		SSBP4	IL36RN
Description		single stranded DNA binding protein 4	interleukin 36 receptor antagonist
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Region Extracellular Space Cytoplasm
	Molecular Function	Single-stranded DNA Binding Protein Binding	Cytokine Activity Interleukin-1 Receptor Binding Interleukin-1 Receptor Antagonist Activity Protein Binding
	Biological Process	Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Cytokine-mediated Signaling Pathway Inflammatory Response To Antigenic Stimulus Inflammatory Response Cytokine-mediated Signaling Pathway Antifungal Humoral Response Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-17 Production Negative Regulation Of Interleukin-6 Production Innate Immune Response Cellular Response To Lipopolysaccharide
Pathways			Interleukin-36 pathway
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 30820047) Basophil count ( 32888494) Breast cancer ( 23535729) Intake of total sugars ( 31005972) Monocyte count ( 27863252) Systemic lupus erythematosus ( 33536424 28714469)	Menstruation quality of life impact (dysmenorrhea) ( 29855537) Pain medicine use during menstruation ( 29855537) Stroke ( 26089329)
Interacting Genes		8 interacting genes: IL36RN LDB1 LDB2 MYO15B PIK3R3 PIN1 SPG21 TFAP2B	18 interacting genes: AGR2 AP3M1 CNOT4 CRACR2B DDIT4L HPCA INCA1 IRAK4 MCM6 REL SH2B2 SKIL SSBP2 SSBP3 SSBP4 UBL4B ZKSCAN4 ZNF512B
Entrez ID		170463	26525
HPRD ID		09579	16112
Ensembl ID		ENSG00000130511	ENSG00000136695
Uniprot IDs		Q9BWG4	A0A024R518 Q9UBH0
PDB IDs			4P0J 4P0K 4P0L
Enriched GO Terms of Interacting Partners?
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