IFNLR1 and BRICD5

Data Source:
BioGRID (two hybrid)

		IFNLR1	BRICD5
Description		interferon lambda receptor 1	BRICHOS domain containing 5
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Interleukin-28 Receptor Complex	Extracellular Space Integral Component Of Membrane
	Molecular Function	Cytokine Receptor Activity Protein Binding	Protein Binding
	Biological Process	Mucosal Immune Response Negative Regulation Of Cell Population Proliferation Cytokine-mediated Signaling Pathway Response To Type III Interferon Regulation Of Defense Response To Virus By Host Defense Response To Virus	Regulation Of Cell Population Proliferation
Pathways		Other interleukin signaling Interleukin-20 family signaling
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Inflammatory skin disease ( 25574825) Molybdenum levels ( 26025379) Psoriasis vulgaris ( 26626624)
Interacting Genes		7 interacting genes: ANKRD46 BRICD5 CTXN3 IFNL1 IFNL2 LSM8 PAEP	41 interacting genes: AQP6 ARL13B BIK CD69 CD79A CLEC2D CLRN1 CREB3L1 FKBP7 HHLA2 HSD17B13 ICAM3 IFNGR2 IFNLR1 IL27RA KIR2DL3 KLRC1 LMNA LRRC25 LRRC4C MRM1 MTIF3 MUC1 NEMP1 PLEKHO1 PSCA PVR SCN3B SGCB SGPL1 SIGLEC9 SLAMF6 SLC18A1 SLC18A2 SORT1 SYNE4 TMEM234 TMEM248 TMEM79 TMPRSS2 TMX2
Entrez ID		163702	283870
HPRD ID		09589	14482
Ensembl ID		ENSG00000185436	ENSG00000182685
Uniprot IDs		Q8IU57	Q6PL45
PDB IDs		3OG4 3OG6 5IXD 5IXI 5L04 5T5W
Enriched GO Terms of Interacting Partners?
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