IFNLR1 and ANKRD46

Data Source:
BioGRID (two hybrid)

		IFNLR1	ANKRD46
Description		interferon lambda receptor 1	ankyrin repeat domain 46
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Interleukin-28 Receptor Complex	Integral Component Of Membrane
	Molecular Function	Cytokine Receptor Activity Protein Binding
	Biological Process	Mucosal Immune Response Negative Regulation Of Cell Population Proliferation Cytokine-mediated Signaling Pathway Response To Type III Interferon Regulation Of Defense Response To Virus By Host Defense Response To Virus
Pathways		Other interleukin signaling Interleukin-20 family signaling
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Inflammatory skin disease ( 25574825) Molybdenum levels ( 26025379) Psoriasis vulgaris ( 26626624)	Atrioventricular conduction ( 21041692) Body mass index ( 26426971) Percentage gas trapping ( 26030696)
Interacting Genes		7 interacting genes: ANKRD46 BRICD5 CTXN3 IFNL1 IFNL2 LSM8 PAEP	61 interacting genes: AMIGO1 APH1A AQP6 ARL13B BIK BSCL2 C16orf54 CD22 CD46 CLDN20 CLDN7 CLEC4D CRB3 CREB3L1 CXADR CYB561 EBP EFNB1 EFNB2 ELOVL4 FAM174A FAM209A GOLM1 GPR152 GPR42 HSD17B11 HSD17B13 IFNLR1 KASH5 KIR2DL3 LAMTOR5 LDLRAD1 LRRC25 MFF MMGT1 MUC1 NCAPH2 NSG2 PLPP4 PVR RELL2 RETREG3 SCN3B SECTM1 SHISA3 SLC10A6 SLC16A2 SLC18A1 SLC39A9 ST6GALNAC6 STX1A STX2 STX4 SUSD3 THAP4 TIMMDC1 TMEM248 TMEM31 TMEM45B TMEM79 TMPRSS2
Entrez ID		163702	157567
HPRD ID		09589	14103
Ensembl ID		ENSG00000185436	ENSG00000186106
Uniprot IDs		Q8IU57	A0A024R9E1 A0A024R9G2 B3KT99 Q86W74
PDB IDs		3OG4 3OG6 5IXD 5IXI 5L04 5T5W
Enriched GO Terms of Interacting Partners?
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