NKX2-3 and ZNF212

Data Source:
BioGRID (two hybrid)

		NKX2-3	ZNF212
Description		NK2 homeobox 3	zinc finger protein 212
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Cellular_component Nucleus	Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding
	Biological Process	Leukocyte Homeostasis Plasma Cell Differentiation Regulation Of Transcription By RNA Polymerase II Triglyceride Metabolic Process Biological_process Gland Morphogenesis Cell Differentiation Macrophage Differentiation Regulation Of Cell Population Proliferation Odontogenesis Of Dentin-containing Tooth CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Lymph Node Development Spleen Development Peyer's Patch Development Post-embryonic Digestive Tract Morphogenesis Leukocyte Migration	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 23749187) Autoimmune thyroid disease ( 32581359) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Colorectal cancer ( 25990418 30529582 24737748) Colorectal cancer or advanced adenoma ( 30510241) Crohn's disease ( 18587394 25489960 28067908 17554261 22412388 17554300 21102463) Dental caries ( 23064961) Granulocyte percentage of myeloid white cells ( 27863252) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Hypothyroidism ( 27182965) Inflammatory bowel disease ( 28067908 23128233) Leukocyte telomere length ( 31171785) Mean corpuscular hemoglobin ( 27863252) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) Pediatric autoimmune diseases ( 26301688) Red blood cell traits ( 23222517) Ulcerative colitis ( 28067908 20228798 20228799)	Metabolite levels ( 23823483)
Interacting Genes		3 interacting genes: GTF2A1L SRF ZNF212	30 interacting genes: - ATF3 ATF4 BYSL CREB3L2 CSK DPF2 DUSP6 FAM90A1 FHL2 GAS8 GNL1 GYS1 HBP1 KANK2 MLH1 NFKBIA NKX2-3 PPARGC1B PRKAA2 PTP4A1 RND1 SAP30BP SF3A3 SUV39H2 ZNF3 ZNF331 ZNF408 ZNF783 ZZZ3
Entrez ID		159296	7988
HPRD ID		05992	03859
Ensembl ID		ENSG00000119919	ENSG00000170260
Uniprot IDs		Q8TAU0	A0A090N8N3 B3KQE6 Q9UDV6
PDB IDs
Enriched GO Terms of Interacting Partners?
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