CYC1 and UQCRFS1

Data Source:
HPRD (in vitro)

		CYC1	UQCRFS1
Description		cytochrome c1	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
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GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex III Membrane Integral Component Of Membrane	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex III Mitochondrial Respiratory Chain Complex IV Integral Component Of Membrane
	Molecular Function	Protein Binding Heme Binding Metal Ion Binding	Protein Binding Ubiquinol-cytochrome-c Reductase Activity Oxidoreductase Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Response To Glucagon	Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Respiratory Electron Transport Chain Mitochondrial Respiratory Chain Complex III Assembly
Pathways		Mitochondrial protein import Respiratory electron transport	Respiratory electron transport
Drugs		2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin 5-Heptyl-6-hydroxy-1,3-benzothiazole-4,7-dione (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2	2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin 5-Heptyl-6-hydroxy-1,3-benzothiazole-4,7-dione (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2
Diseases
GWAS		Asthma ( 31959851) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494)	Disease progression in age-related macular degeneration ( 29346644) Methadone dose in opioid dependence ( 28115739)
Interacting Genes		2 interacting genes: CYCS UQCRFS1	4 interacting genes: CYC1 HTR6 RELB SOX5
Entrez ID		1537	7386
HPRD ID		00480	01874
Ensembl ID		ENSG00000179091	ENSG00000169021
Uniprot IDs		P08574	P47985
PDB IDs		5XTE 5XTH 5XTI	5XTE 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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