ZMAT2 and TNIP1

Data Source:
BioGRID (two hybrid)

		ZMAT2	TNIP1
Description		zinc finger matrin-type 2	TNFAIP3 interacting protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome	Nucleoplasm Cytosol
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding	Protein Binding Polyubiquitin Modification-dependent Protein Binding Identical Protein Binding Mitogen-activated Protein Kinase Binding
	Biological Process	MRNA Splicing, Via Spliceosome	MyD88-dependent Toll-like Receptor Signaling Pathway Translation Defense Response Inflammatory Response Leukocyte Cell-cell Adhesion Glycoprotein Biosynthetic Process Protein Deubiquitination Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Viral Genome Replication Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Inflammatory Response Negative Regulation Of ERK1 And ERK2 Cascade Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Positive Regulation Of Protein Deubiquitination
Pathways			Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Major depressive disorder ( 27479909) Refractive error ( 32231278) Schizophrenia ( 28991256 29483656) Serum immune biomarker levels ( 32066700) Systolic blood pressure ( 30224653)	Amyotrophic lateral sclerosis ( 29566793) Autoimmune traits (pleiotropy) ( 30572963) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 28067908) Cutaneous psoriasis ( 26626624) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Inflammatory bowel disease ( 28067908 23128233) Inflammatory skin disease ( 25574825) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Myasthenia gravis ( 23055271) Neutrophil percentage of granulocytes ( 27863252) Psoriasis ( 25854761 25903422 25574825 23143594 19169254) Psoriasis vulgaris ( 26626624 29031612) Psoriatic arthritis ( 26626624) Rheumatoid arthritis ( 30572963) Rheumatoid arthritis (ACPA-positive) ( 23143596) SjÃ¶gren's syndrome ( 24097067) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus ( 27399966 26606652 23273568 26502338 28714469 19838193 19838195) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic sclerosis ( 21750679 31672989 30572963 29293537) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655)
Interacting Genes		40 interacting genes: AK8 AMH BICD2 CALCOCO1 CBY2 CCDC57 CDR2 CEP76 ERBB2 FSD2 FXR1 FXR2 GOLGA2 GOLGA6L9 GRIPAP1 HAP1 HMBOX1 IKZF1 KANK2 KRT40 LZTS2 MEOX2 MTUS2 NAB2 NUTF2 PHC2 PICK1 PRPH SPAG5 SSX2IP TFEC TFIP11 TNIP1 TRAF2 TRIM36 TRIM37 TSEN15 VPS52 ZBTB14 ZBTB8A	95 interacting genes: ABHD17A ADH6 AP1M1 BYSL C8orf33 CCDC112 CCDC121 CCNG1 CDC23 CDC37 CDIP1 CDKN1A CFAP53 CYSRT1 DAZAP2 DPPA4 EFEMP1 EHHADH ELOA FAM161A FAM168A FUS GABARAPL1 GABARAPL2 GIT2 GTF2B GTF2H1 HDAC1 HDDC3 IKBKG KIFC3 KRTAP19-3 KRTAP19-5 KRTAP19-7 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 LENG8 LITAF MAGEB18 MAGEH1 MAP1LC3A MAP1LC3B MAP1LC3C MAP3K1 MAPK1 MAPK10 MCM10 MCRS1 MOB1B MOB3C MORF4L1 MORF4L2 NDC80 NFKB1 NIFK NME7 NOD2 OPTN PIBF1 PIN1 PNKP RABAC1 RALBP1 RARA RARG RBFOX1 RNF11 RNF8 RPL5 S100B SELPLG SHTN1 SNIP1 SPATA2 SUMO2 SYT6 TAX1BP1 TCEA2 TCEANC TCEANC2 TNFAIP3 TNIP3 TSG101 TTC39A TTF2 TXLNA TYRO3 UBC VPS33B WTAP ZBTB25 ZMAT2 ZNHIT1
Entrez ID		153527	10318
HPRD ID		08094	09216
Ensembl ID		ENSG00000146007	ENSG00000145901
Uniprot IDs		Q96NC0	A0A0A0MRZ4 A8K4N4 B7Z8K2 Q15025
PDB IDs		5O9Z 6AHD
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?