CCDC50 and ARRDC3

Data Source:
BioGRID (two hybrid)

		CCDC50	ARRDC3
Description		coiled-coil domain containing 50	arrestin domain containing 3
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GO Annotations	Cellular Component	Cytosol	Cytoplasm Lysosome Endosome Early Endosome Plasma Membrane
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	Protein Binding Beta-3 Adrenergic Receptor Binding
	Biological Process	Sensory Perception Of Sound	Temperature Homeostasis Protein Transport Negative Regulation Of Heat Generation Skin Development Positive Regulation Of Ubiquitin-protein Transferase Activity Fat Pad Development Negative Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Negative Regulation Of Locomotion Involved In Locomotory Behavior Negative Regulation Of Cold-induced Thermogenesis
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease biomarkers ( 23562540) Lung cancer in never smokers ( 28604730)	Breast cancer ( 29059683 25038754) Breast cancer (prognosis) ( 23319801) Breast cancer (survival) ( 25526632) Platelet distribution width ( 32888494) Subcutaneous adipose tissue ( 22589738)
Interacting Genes		7 interacting genes: ARRDC3 RIPK1 RNF8 RPS3A SH3GL1 TNFAIP3 UBC	40 interacting genes: ADRB2 BAG3 BCL6 CCDC50 CDA DCUN1D1 EFEMP2 EPN2 F2R FAM90A1 HPGDS ITCH MAGI2 MORF4L1 NEDD4L OPTN OTUB2 PDCD6IP PHF1 PRKAA2 RABGEF1 RACK1 RAD18 SMARCD1 STAM2 TNFAIP3 TOLLIP TRIM42 UBA52 UBAC1 UBASH3A UBE2D1 UBE2D2 UBE2E2 UBE2E3 UBQLN2 WWOX WWP1 WWP2 ZRANB1
Entrez ID		152137	57561
HPRD ID		06463	09810
Ensembl ID		ENSG00000152492	ENSG00000113369
Uniprot IDs		Q8IVM0	Q96B67
PDB IDs		6LAN	4N7H 4R7V 4R7X
Enriched GO Terms of Interacting Partners?
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